Delbem Alberto Carlos Botazzo, Cury Jaime A
Department of Pediatric Dentistry, Faculty of Dentistry of Araçatuba, UNESP, São Paulo, Brazil.
Am J Dent. 2002 Jun;15(3):169-72.
To evaluate the effect of time of fluoride application gel, acidulated or neutral, on in vitro enamel resistance to demineralization and fluoride uptake.
One hundred and ninety-two human enamel blocks were used in this study and 144 were treated with fluoride gel, acidulated or neutral, for 1 or 4 minutes. Ninety-six blocks treated with fluoride and 24 control blocks were submitted to a high cariogenic challenge. After the pH-cycling, enamel demineralization was assessed by surface and cross-sectional microhardness. Fluoride in the enamel blocks was also determined after removing an enamel layer by etching acid.
Acidulated fluoride gel formed more fluoride in enamel than neutral gel (P<0.05), and it was also more efficient in reducing the demineralization of the enamel blocks submitted to a cariogenic challenge than the neutral one (P<0.05). It was found that the time of application was significant in terms of fluoride uptake, but it did not render the enamel more resistant to demineralization.
评估应用酸化或中性含氟凝胶的时间对体外牙釉质抗脱矿及氟摄取的影响。
本研究使用了192个人类牙釉质块，其中144个用酸化或中性含氟凝胶处理1或4分钟。96个经氟处理的牙釉质块和24个对照牙釉质块接受高致龋性挑战。经过pH循环后，通过表面和横截面显微硬度评估牙釉质脱矿情况。在用蚀刻酸去除牙釉质层后，还测定了牙釉质块中的氟含量。
酸化含氟凝胶在牙釉质中形成的氟比中性凝胶更多（P<0.05），并且在降低接受致龋性挑战的牙釉质块的脱矿方面也比中性凝胶更有效（P<0.05）。结果发现，应用时间在氟摄取方面具有显著意义，但并未使牙釉质更抗脱矿。
