Puri Neerja
Department of Dermatology, Punjab Health Systems Corporation, Ludhiana, Punjab, India.
J Cutan Aesthet Surg. 2015 Jan-Mar;8(1):42-5. doi: 10.4103/0974-2077.155082.
There is a paucity of studies on the use of chemical peels for acne scars among the Asian population. A trichloroacetic acid (TCA) and Jessner's combination chemical peel, originally described by Monheit, is said to be better than a TCA peel alone.
The aim of the study was to compare the efficacy of 20% TCA and Jessner's solution versus 20% TCA alone for the treatment of acne scars.
: The patients were divided into two groups of 25 patients each. Chemical peeling was done in both the groups. In Group I, chemical peeling with Jessner's peel followed by 20% TCA was done and in Group II patients chemical peeling with 20% TCA peel alone was done.
In Group I (Jessner's peel and 20% TCA), mild improvement of acne scars was seen in 8% cases, moderate improvement in 32% cases and marked improvement of acne scars was seen in 60% patients. In Group II (20% TCA), mild improvement of acne scars was seen in 32% cases, moderate improvement in 40% cases and marked improvement of acne scars was seen in 28% patients. But, the difference in improvement of acne scars was not statistically significant in both the groups (P value > 0.05).
针对亚洲人群使用化学换肤术治疗痤疮瘢痕的研究较少。最初由莫恩海特描述的三氯乙酸(TCA)与杰斯纳溶液联合化学换肤术,据说比单纯使用TCA换肤术效果更好。
本研究旨在比较20% TCA与杰斯纳溶液联合应用和单纯使用20% TCA治疗痤疮瘢痕的疗效。
患者被分为两组,每组25例。两组均进行化学换肤术。第一组先使用杰斯纳溶液进行化学换肤,随后使用20% TCA;第二组患者仅使用20% TCA进行化学换肤。
在第一组(杰斯纳溶液和20% TCA)中,8%的病例痤疮瘢痕有轻度改善,32%的病例有中度改善,60%的患者痤疮瘢痕有显著改善。在第二组(20% TCA)中,32%的病例痤疮瘢痕有轻度改善,40%的病例有中度改善,28%的患者痤疮瘢痕有显著改善。但是,两组痤疮瘢痕改善情况的差异无统计学意义(P值>0.05)。