Turk Ugur, Turk Bengu Gerceker, Yılmaz Suzan Guven, Tuncer Esref, Alioğlu Emin, Dereli Tugrul
Department of Cardiology, Central Hospital, Bayrakli, Izmir, Turkey.
Department of Dermatology, Ege University Medical Faculty, Bornova, Izmir, Turkey.
Middle East Afr J Ophthalmol. 2015 Apr-Jun;22(2):258-60. doi: 10.4103/0974-9233.154411.
Amiodarone is an antiarrhythmic medication that can adversely effect various organs including lungs, thyroid gland, liver, eyes, skin, and nerves. The risk of adverse effects increases with high doses and prolonged use. We report a 54-year-old female who presented with multiorgan toxicity after 8 months of low dose (200 mg/day) amiodarone treatment. The findings of confocal microscopy due to amiodarone-induced keratopathy are described. Amiodarone may cause multiorgan toxicity even at lower doses and for shorter treatment periods.
胺碘酮是一种抗心律失常药物,可对包括肺、甲状腺、肝脏、眼睛、皮肤和神经在内的各种器官产生不良影响。高剂量和长期使用会增加不良反应的风险。我们报告一名54岁女性,在低剂量(200毫克/天)胺碘酮治疗8个月后出现多器官毒性。描述了因胺碘酮诱发角膜病变的共聚焦显微镜检查结果。即使在较低剂量和较短治疗期,胺碘酮也可能导致多器官毒性。