Choi Donchan, Roh Hyun Soo, Kang Dong Won, Lee Jong Seok
Department of Life Science, College of Environmental Sciences, Yong-In University, Yongin 449-714, Republic of Korea.
Dev Reprod. 2014 Mar;18(1):57-64. doi: 10.12717/DR.2014.18.1.057.
The flower buds of Syzygium aromaticum (clove) have been used as traditional medicine for the treatment of male sexual disorders in Asian countries. Recently, there are some reports about the effects of the clove on reproductive activities in mammals. Therefore, its effect on testicular function was examined in male golden hamsters whose reproductive activity is inhibited by photoperiod such as winter climate. The male animals were given by daily oral administrations (56 consecutive days) in three doses (4 mg, 20 mg, and 100 mg/kg BW) of the alcoholic extract of the clove. Generally lower dose (4 mg) of the extract continued to keep the reproductive activities of testes. The both middle and high doses (20 mg and 100 mg) of the extract completely inhibited the testicular activity in some animals. Taken together, these results suggest a possible biphasic action of alcoholic extract of Syzygium aromaticum flower bud on testicular function.
在亚洲国家，丁香的花芽已被用作治疗男性性功能障碍的传统药物。最近，有一些关于丁香对哺乳动物生殖活动影响的报道。因此，在生殖活动受光周期（如冬季气候）抑制的雄性金黄仓鼠中研究了其对睾丸功能的影响。给雄性动物每日口服（连续56天）三种剂量（4毫克、20毫克和100毫克/千克体重）的丁香醇提取物。一般来说，较低剂量（4毫克）的提取物能持续维持睾丸的生殖活动。中等剂量和高剂量（20毫克和100毫克）的提取物在一些动物中完全抑制了睾丸活动。综上所述，这些结果表明丁香花芽醇提取物对睾丸功能可能具有双相作用。
