Lorenc J, Kościuk N
Przegl Lek. 1989;46(9):681-5.
In 150 patients with cerebral insult and in 153 subjects of the control group the studies have been performed with an aim to establish the biochemical evaluation of the arteriosclerotic threat. The cholesterol, phospholipid, triglyceride and apo B concentration in the serum as well as quantitative evaluation of the HDL and LDL fractions were involved. The sex-related differences have been found so far as apo B and lipid serum components are concerned. The most characteristic alterations have been showed in the HDL fraction. In the all patients studied the significant decrease in the HDL-CH concentration as well as an increased HDL-PL/HDL-CH index has been noted suggesting changes in the HDL subfraction leading to the diminished concentration of anti-atherogenic HDL2 fraction.
对150例脑损伤患者和153名对照组受试者进行了研究，目的是建立动脉粥样硬化风险的生化评估。检测了血清中的胆固醇、磷脂、甘油三酯和载脂蛋白B浓度，以及高密度脂蛋白（HDL）和低密度脂蛋白（LDL）组分的定量评估。就载脂蛋白B和血脂成分而言，发现了与性别相关的差异。最显著的变化出现在HDL组分中。在所研究的所有患者中，均观察到HDL-胆固醇（HDL-CH）浓度显著降低，以及HDL-磷脂（HDL-PL）/HDL-CH指数升高，这表明HDL亚组分发生了变化，导致抗动脉粥样硬化的HDL2组分浓度降低。
