Rosenbaum James T
Casey Eye Institute, Oregon Health & Science University, 3181 SW San Jackson PK Rd, Portland, OR, 97239, USA,
Clin Rheumatol. 2015 Jun;34(6):999-1002. doi: 10.1007/s10067-015-2960-8. Epub 2015 May 8.
Uveitis is a common complication of spondyloarthritis. The "phenotype" of the uveitis characteristic of ankylosing spondylitis (sudden onset, anterior, unilateral, recurrent, more often male) may differ from the phenotype often seen with either psoriatic arthritis or inflammatory bowel disease (insidious onset, anterior and intermediate, bilateral, chronic, and/or more often female). The frequency of uveitis is also much greater in association with ankylosing spondylitis than with either inflammatory bowel disease or psoriasis. Uveitis may affect the choice of therapy and can rarely be a complication of therapy. Uveitis and arthritis also co-exist in several animal models.
葡萄膜炎是脊柱关节炎的常见并发症。强直性脊柱炎特征性葡萄膜炎的“表型”(突然发作、前部、单侧、复发性、男性更为常见)可能与银屑病关节炎或炎症性肠病常见的表型不同(隐匿性发作、前部和中间部、双侧、慢性和/或女性更为常见)。与炎症性肠病或银屑病相比,葡萄膜炎在强直性脊柱炎中的发生率也高得多。葡萄膜炎可能会影响治疗方案的选择,并且很少会成为治疗的并发症。在几种动物模型中也存在葡萄膜炎和关节炎并存的情况。