Wayangankar Siddharth A, Kennedy Kevin F, Aronow Herbert D, Rundback John, Tafur Alfonso, Drachman Douglas, Patel Bhavin, Sivaram Chittur A, Latif Faisal
From the Cleveland Clinic Foundation, OH (S.A.W.); Mid America Heart and Vascular Institute, St. Luke's Hospital, Kansas City, MO (K.F.K.); Michigan Heart and Vascular Institute, Ypsilanti (H.D.A.); Holy Name Medical Center, Teaneck, NJ (J.R.); University of Oklahoma Health Sciences Center and Veterans' Affairs Medical Center (A.T., B.P., C.A.S., F.L.); and Massachusetts General Hospital, Boston (D.D.).
Stroke. 2015 Jun;46(6):1525-32. doi: 10.1161/STROKEAHA.115.009013. Epub 2015 May 7.
It is not known whether racial or ethnic disparities observed with other revascularization procedures are also seen with carotid artery stenting (CAS) and endarterectomy (CEA).
We compared the utilization and outcomes of CAS and CEA across racial/ethnic groups within the CARE Registry between May 2007 and December 2012.
Between 2007 and 2012, of the 13 129 patients who underwent CAS, majority were non-Hispanic whites (89.3%), followed by blacks (4.4%), Hispanics (4.3%), and other groups (2.0%). A similar distribution was observed among the 10 953 patients undergoing CEA (non-Hispanic whites, 92.6%; blacks, 3.5%; Hispanics, 2.8%; and other groups, 1.1%). During this time period, a trend toward proportionate increase in CAS utilization was observed in non-Hispanic whites and other groups, whereas the opposite was observed among Hispanics and blacks. This trend persisted even when hospitals performing both CAS and CEA were exclusively analyzed. Adherence to antiplatelet and statin therapy was significantly lower among blacks post CEA. In-hospital major adverse cardiac and cerebrovascular events remained comparable across groups post CAS and CEA. At 30 days, the incidence of stroke (7.2%) and major adverse cardiac and cerebrovascular events (8.8%) was higher among blacks post CEA (P<0.05), after risk adjustment.
During the study period, utilization of CAS and CEA was highest among non-Hispanic whites. There was a trend toward increased CAS utilization over time among non-Hispanic whites and other groups, and a trend toward increased CEA utilization among Hispanics and blacks. In-hospital major adverse cardiac and cerebrovascular events remained comparable between groups, whereas 30-day major adverse cardiac and cerebrovascular events were significantly higher in blacks.
目前尚不清楚在其他血管重建手术中观察到的种族或民族差异在颈动脉支架置入术(CAS)和颈动脉内膜切除术(CEA)中是否也存在。
我们比较了2007年5月至2012年12月期间CARE注册中心不同种族/民族群体中CAS和CEA的使用情况及治疗结果。
2007年至2012年期间,在13129例行CAS的患者中,大多数是非西班牙裔白人(89.3%),其次是黑人(4.4%)、西班牙裔(4.3%)和其他群体(2.0%)。在10953例行CEA的患者中也观察到类似的分布(非西班牙裔白人,92.6%;黑人,3.5%;西班牙裔,2.8%;其他群体,1.1%)。在此期间,非西班牙裔白人和其他群体中CAS使用比例有增加的趋势,而西班牙裔和黑人中则相反。即使仅分析同时进行CAS和CEA的医院,这一趋势仍然存在。CEA术后黑人抗血小板和他汀类药物治疗的依从性显著较低。CAS和CEA术后各群体住院期间主要不良心脑血管事件发生率相当。在风险调整后,CEA术后30天时黑人中风发生率(7.2%)和主要不良心脑血管事件发生率(8.8%)较高(P<0.05)。
在研究期间,非西班牙裔白人中CAS和CEA的使用率最高。非西班牙裔白人和其他群体中CAS的使用随时间有增加趋势,而西班牙裔和黑人中CEA的使用有增加趋势。各群体住院期间主要不良心脑血管事件发生率相当,而黑人30天主要不良心脑血管事件发生率显著更高。