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电子医疗记录基因组学与环境暴露研究网络(eMERGE)信息按钮项目中用于编写和改编基因组医学内容的模板。

A Template for Authoring and Adapting Genomic Medicine Content in the eMERGE Infobutton Project.

作者信息

Overby Casey L, Rasmussen Luke V, Hartzler Andrea, Connolly John J, Peterson Josh F, Hedberg RoseMary E, Freimuth Robert R, Shirts Brian H, Denny Joshua C, Larson Eric B, Chute Christopher G, Jarvik Gail P, Ralston James D, Shuldiner Alan R, Starren Justin, Kullo Iftikhar J, Tarczy-Hornoch Peter, Williams Marc S

机构信息

Program for Personalized and Genomic Medicine and Department of Medicine, University of Maryland, Baltimore, MD ; Center for Health-related Informatics and Bioimaging, University of Maryland, Baltimore, MD.

Department of Preventive Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.

出版信息

AMIA Annu Symp Proc. 2014 Nov 14;2014:944-53. eCollection 2014.

Abstract

The Electronic Medical Records and Genomics (eMERGE) Network is a national consortium that is developing methods and best practices for using the electronic health record (EHR) for genomic medicine and research. We conducted a multi-site survey of information resources to support integration of pharmacogenomics into clinical care. This work aimed to: (a) characterize the diversity of information resource implementation strategies among eMERGE institutions; (b) develop a master template containing content topics of important for genomic medicine (as identified by the DISCERN-Genetics tool); and (c) assess the coverage of content topics among information resources developed by eMERGE institutions. Given that a standard implementation does not exist and sites relied on a diversity of information resources, we identified a need for a national effort to efficiently produce sharable genomic medicine resources capable of being accessed from the EHR. We discuss future areas of work to prepare institutions to use infobuttons for distributing standardized genomic content.

摘要

电子病历与基因组学(eMERGE)网络是一个全国性联盟,正在开发将电子健康记录(EHR)用于基因组医学和研究的方法及最佳实践。我们开展了一项信息资源的多中心调查,以支持将药物基因组学整合到临床护理中。这项工作旨在:(a)描述eMERGE机构间信息资源实施策略的多样性;(b)开发一个包含对基因组医学重要的内容主题的主模板(由DISCERN-遗传学工具确定);(c)评估eMERGE机构开发的信息资源中内容主题的覆盖范围。鉴于不存在标准实施方法且各机构依赖多种信息资源,我们确定需要开展一项全国性工作,以高效生产能够从电子健康记录中获取的可共享基因组医学资源。我们讨论了未来的工作领域,以使各机构做好使用信息按钮来分发标准化基因组内容的准备。

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