Nucleotide sequence analysis of the capsid genes and the right-hand terminal palindrome of porcine parvovirus, strain NADL-2.

The genome of the porcine parvovirus, strain NADL-2, has been cloned and the sequence of map units 28 to 100, which is 3670 bp in length and contains the capsid coding regions and the right-hand terminal palindrome, has been determined. The sequence shows extensive homology with other parvoviruses such as MVM, H-1, CPV, and FPV in the capsid coding region. Given the information available from these sequences, the regulatory and capsid coding regions for PPV have been proposed and the amino acid sequences of capsid proteins compared. The right end, which has a 188-nucleotide-long imperfect palindromic sequence, has an organization similar to that of other parvoviruses and the homologies in this region with other parvoviruses correspond to the homologies observed in the rest of the respective genomes.