Szaflarska-Popławska Anna
Department of Paediatric Endoscopy and Gastrointestinal Function Testing, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Prz Gastroenterol. 2015;10(1):12-7. doi: 10.5114/pg.2014.47503. Epub 2015 Jan 14.
This is a selective review of the literature concerning the methods of celiac disease treatment, which can be an alternative to a gluten-free diet. The most advanced studies are devoted to the larazotide acetate (AT-1001, human zonulin inhibitor) and prolyl-endopeptidases degrading toxic gluten peptides (ALV003, AN-PEP). It is estimated that they will be registered within a few years. They will not become an alternative to the gluten-free diet but rather a supplement to it, which will enable patients to ease the nutritional restrictions.
这是一篇关于乳糜泻治疗方法的文献综述，这些方法可作为无麸质饮食的替代方案。最前沿的研究集中在醋酸拉佐肽（AT-1001，人zonulin抑制剂）和降解有毒麸质肽的脯氨酰内肽酶（ALV003，AN-PEP）上。据估计，它们将在几年内获批上市。它们不会成为无麸质饮食的替代品，而是其补充剂，这将使患者能够减轻营养限制。
