Schoen Lucy, Santoro Jonathan D, Milla Carlos, Bhargava Sumit
Stanford University School of Medicine, 291 Campus Drive, Li Ka Shing Building, Stanford, CA 94305-5101, USA.
Department of Pediatrics, Stanford Children's Hospital, 725 Welch Road, Palo Alto, CA 94304, USA.
Case Rep Pulmonol. 2015;2015:984171. doi: 10.1155/2015/984171. Epub 2015 Apr 15.
Nocardia spp. are bacteria of low virulence that cause infection classically in immunocompromised hosts with the lungs as the primary site of infection in the majority of cases. Patients with cystic fibrosis have pulmonary disease characterized by frequent and progressive bacterial infections. Reports of Nocardia spp. isolation in CF are rare in the literature and may represent colonization or active infection, the significance and optimal treatment of which are unknown. We report the second case to date of Nocardia transvalensis pulmonary infection in an immunocompetent patient with CF and the first in a child under the age of eighteen.
诺卡菌属是低毒力细菌，通常在免疫功能低下的宿主中引起感染，大多数情况下肺部是主要感染部位。囊性纤维化患者的肺部疾病特征为频繁且进行性的细菌感染。文献中关于在囊性纤维化患者中分离出诺卡菌属的报道很少，可能代表定植或活动性感染，其意义及最佳治疗方法尚不清楚。我们报告了迄今为止第二例免疫功能正常的囊性纤维化患者发生的特氏诺卡菌肺部感染病例，也是首例18岁以下儿童患者。
