Horev Amir, Haim Alon, Zvulunov Alex
Pediatr Endocrinol Rev. 2015 Mar;12(3):308-10.
ince 2008, propranolol has become the first line therapy for infantile hemangiomas. Due to the fact that infantile hemangiomas are the most common vascular tumors of infancy, the use of systemic propranolol has been dramatically increased in the last few years. The reported adverse effects of propranolol in the treatment of infantile hemangiomas included symptomatic hypoglycemia. In this review we will summarize those reports and will offer guidelines for prevention of hypoglycemia secondary to propranolol therapy.
自2008年以来,普萘洛尔已成为婴儿血管瘤的一线治疗药物。由于婴儿血管瘤是婴儿期最常见的血管肿瘤,在过去几年中,全身性普萘洛尔的使用量大幅增加。据报道,普萘洛尔治疗婴儿血管瘤的不良反应包括症状性低血糖。在本综述中,我们将总结这些报告,并提供预防普萘洛尔治疗继发性低血糖的指南。