什么是实用临床试验？ - Suppr

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What is a pragmatic clinical trial?

作者信息

Williams Hywel C, Burden-Teh Esther, Nunn Andrew J

机构信息

Centre of Evidence-Based Dermatology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.

出版信息

J Invest Dermatol. 2015 Jun;135(6):1-3. doi: 10.1038/jid.2015.134.

DOI:10.1038/jid.2015.134

PMID:25964272

Abstract

摘要

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Br J Dermatol. 2015 Jul;173(1):227-34. doi: 10.1111/bjd.13729. Epub 2015 May 26.

Clinical trials submitted to the JID: place your bet and show us your hand.

J Invest Dermatol. 2015 Feb;135(2):325-327. doi: 10.1038/jid.2014.478.

Penicillin to prevent recurrent leg cellulitis.青霉素预防腿部蜂窝织炎复发。

N Engl J Med. 2013 May 2;368(18):1695-703. doi: 10.1056/NEJMoa1206300.

Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial.抗白细胞介素-17受体抗体AMG 827在中度至重度银屑病患者中可引发快速临床反应：一项I期随机安慰剂对照试验的结果

J Invest Dermatol. 2012 Oct;132(10):2466-2469. doi: 10.1038/jid.2012.163. Epub 2012 May 24.

Trials. 2012 Apr 27;13:50. doi: 10.1186/1745-6215-13-50.

The growth of clinical trials and systematic reviews in informing dermatological patient care.临床试验和系统评价在为皮肤病患者护理提供信息方面的增长。

J Invest Dermatol. 2012 Mar;132(3 Pt 2):1008-17. doi: 10.1038/jid.2011.337. Epub 2011 Nov 3.

Comparative effectiveness research: a report from the Institute of Medicine.比较效果研究：医学研究所的一份报告。

Ann Intern Med. 2009 Aug 4;151(3):203-5. doi: 10.7326/0003-4819-151-3-200908040-00125. Epub 2009 Jun 30.

Making trials matter: pragmatic and explanatory trials and the problem of applicability.让试验发挥作用：实用型与解释型试验及适用性问题。

Trials. 2009 Jun 3;10:37. doi: 10.1186/1745-6215-10-37.

A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers.实用-解释性连续统指标总结（PRECIS）：一种帮助试验设计者的工具。

J Clin Epidemiol. 2009 May;62(5):464-75. doi: 10.1016/j.jclinepi.2008.12.011.

Effectiveness and cost-effectiveness of salicylic acid and cryotherapy for cutaneous warts. An economic decision model.水杨酸和冷冻疗法治疗皮肤疣的有效性和成本效益：一项经济决策模型

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