Chauhan B C, Drance S M, Douglas G R, Johnson C A
Department of Ophthalmology, University of British Columbia, Vancouver, Canada.
Am J Ophthalmol. 1989 Dec 15;108(6):636-42. doi: 10.1016/0002-9394(89)90854-4.
We studied the ocular characteristics of 40 pairs of normal-tension and high-tension glaucoma patients who matched closely for the extent of field damage, pupil size, and visual acuity. To determine if there were differences in visual field damage between patients with normal-tension and high-tension glaucoma, we studied characteristics of the areas of the patients' visual fields that were undisturbed. We computed the number of normal locations, the number of clustered normal locations, and the size of the largest cluster of normal locations. The results showed that for an equivalent extent of damage, the individuals in the normal-tension group had greater areas with normal sensitivity, hence more localized damage. A comparison of the patient data to control data showed that paired differences were larger when the normal-tension member of a pair had a larger value in any of the parameters. The results support the hypothesis that glaucoma patients with lower intraocular pressures have more localized damage and those with higher intraocular pressures have more diffuse damage.
我们研究了40对原发性开角型青光眼和原发性闭角型青光眼患者的眼部特征，这些患者在视野损害程度、瞳孔大小和视力方面密切匹配。为了确定原发性开角型青光眼和原发性闭角型青光眼患者在视野损害方面是否存在差异，我们研究了患者视野中未受干扰区域的特征。我们计算了正常位置的数量、聚集正常位置的数量以及最大正常位置簇的大小。结果表明，在同等损害程度下，原发性开角型青光眼组个体具有更大的正常敏感度区域，因此损害更局限。将患者数据与对照数据进行比较表明，当一对患者中开角型青光眼患者在任何参数上的值较大时，配对差异更大。结果支持了以下假设：眼压较低的青光眼患者损害更局限，而眼压较高的患者损害更弥漫。
