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母体补充亚麻籽油对自助餐饮食诱导肥胖大鼠代谢参数的影响。

Effects of Maternal Linseed Oil Supplementation on Metabolic Parameters in Cafeteria Diet-induced Obese Rats.

作者信息

Benaissa Nawel, Merzouk Hafida, Merzouk Sid Ahmed, Narce Michel

机构信息

Laboratory of Physiology and Biochemistry of Nutrition, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University Abou-Bekr Belkaïd, Tlemcen 13000, Algeria.

Department of technical Sciences, Faculty of Engineering, University Abou-Bekr Belkaïd, Tlemcen 13000, Algeria.

出版信息

Biomed Environ Sci. 2015 Apr;28(4):298-302. doi: 10.3967/bes2015.041.

DOI:10.3967/bes2015.041
PMID:25966756
Abstract

Because linseed oil may influence maternal and fetal metabolisms, we investigated its role in the modulation of lipid metabolism in cafeteria diet-induced obese rats and their offspring. Female Wistar rats were fed control or cafeteria food, which were either supplemented or not supplemented with linseed oil (5%) for 1 month before and during gestation. At parturition, serum and tissue lipids and enzyme activities were analyzed. Cafeteria diet induced adverse metabolic alterations in both mothers and offspring. Linseed oil improved metabolic status. In conclusion, linseed oil displayed health benefits by modulating tissue enzyme activities in both obese mothers and their newborns.

摘要

由于亚麻籽油可能会影响母体和胎儿的新陈代谢,我们研究了其在高脂饮食诱导的肥胖大鼠及其后代脂质代谢调节中的作用。雌性Wistar大鼠在妊娠前和妊娠期间1个月喂食对照食物或高脂食物,高脂食物添加或不添加5%的亚麻籽油。分娩时,分析血清和组织脂质及酶活性。高脂饮食在母亲和后代中均引起不良代谢改变。亚麻籽油改善了代谢状况。总之,亚麻籽油通过调节肥胖母亲及其新生儿的组织酶活性显示出健康益处。

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