Wen Xiang, Li Yong, Jiang Xian
a Department of Dermatology , West China Hospital of Sichuan University , Chengdu, Sichuan Province , P. R. China.
J Cosmet Laser Ther. 2016;18(1):12-5. doi: 10.3109/14764172.2015.1039042. Epub 2015 Jul 6.
Different types of Q-switched (QS) lasers have been used successfully to treat nevus of Ota. The purpose of this study was to compare the clinical efficacy and complication of QS alexandrite (QS Alex) laser versus QS neodymium:yttrium aluminum garnet (Nd:YAG) (QS Nd:YAG) laser for bilateral nevus of Ota. Seventeen patients with bilateral nevus of Ota were treated randomly with QS Alex in one half of face and QS Nd:YAG in the other half with an interval of at least 3 months between each. Subjective assessment was made by both patients and dermatologists. Patients were also examined for evidence of complications. All patients experienced improvement (p < 0.05). There was no statistically significant difference between the two sides (p > 0.05). The pain after a short period of laser therapy was more severe for QS Alex than for QS Nd:YAG laser. Vesicles developed in 1 patient after QS Alex therapy. Both QS Alex laser and QS Nd:YAG laser were equally effective at improving bilateral nevus of Ota. Patients tolerate QS Nd:YAG laser better than QS Alex laser.
不同类型的调Q（QS）激光已成功用于治疗太田痣。本研究的目的是比较调Q紫翠宝石（QS Alex）激光与调Q钕：钇铝石榴石（Nd：YAG）（QS Nd：YAG）激光治疗双侧太田痣的临床疗效和并发症。17例双侧太田痣患者，一侧面部随机接受QS Alex激光治疗，另一侧面部接受QS Nd：YAG激光治疗，每次治疗间隔至少3个月。由患者和皮肤科医生进行主观评估。还对患者进行了并发症检查。所有患者均有改善（p<0.05）。两侧之间无统计学显著差异（p>0.05）。短时间激光治疗后，QS Alex激光引起的疼痛比QS Nd：YAG激光更严重。1例患者在接受QS Alex激光治疗后出现水疱。QS Alex激光和QS Nd：YAG激光在改善双侧太田痣方面同样有效。患者对QS Nd：YAG激光的耐受性优于QS Alex激光。
