Department of Surgery, Western Health, Footscray, Victoria, Australia.
Department of Surgery, Western Health, Footscray, Victoria, Australia.
Int J Surg. 2015 Jun;18:220-3. doi: 10.1016/j.ijsu.2015.05.005. Epub 2015 May 9.
Biliary tract disease is a common non-obstetric surgical presentation during pregnancy. Although small international series demonstrate favourable outcomes following laparoscopic cholecystectomy (LC) during pregnancy, there is a paucity of Australian data to complement these findings.
Between 1st January 2003 and 30th June 2013, all patients undergoing planned LC during pregnancy at Western Health were retrospectively identified.
Twenty-two patients underwent planned LC with 3 (13%) cases converted to open surgery. The median maternal age was 31 years (27.8-36) with an estimated median gestational age (EGA) of 19.5 weeks (16.5-23.5). Eighteen (82%) cases were performed during the second trimester. Nine (40%) patients had 2 or more hospital admissions for similar presentations. Twelve (54%) were performed as index cases. Operative indications included 12 (54%) with recurrent biliary colic, five (22%) with acute cholecystitis and 3 (14%) with gallstone pancreatitis. Median operating time for completed LCs was 65 min (60-95). Intra-operative cholangiogram was performed in seven (32%) cases, 5 (71%) of which employed protective uterine lead shielding. There was no fetal loss or uterine injury. Median hospital stay was 3 days (2-7) for completed LCs. Major morbidity occurred in 2 (10%) completed LCs that required a return to theatre. Five (23%) births were lost to follow up. The median time to delivery post-surgery was 13 weeks (11-15). Two (12%) preterm deliveries occurred, with subsequent neonatal complications.
Antenatal laparoscopic cholecystectomy demonstrated comparably safe outcomes. Increasing its utilization to manage symptomatic cholelithiasis during pregnancy may be considered.
胆道疾病是妊娠期常见的非产科外科疾病。尽管国际上有一些小的系列研究表明,在怀孕期间行腹腔镜胆囊切除术(LC)的效果良好,但澳大利亚的数据还不足以补充这些发现。
在 2003 年 1 月 1 日至 2013 年 6 月 30 日期间,回顾性地分析了在 Western Health 行计划性 LC 的所有孕妇病例。
22 例孕妇行计划性 LC,其中 3 例(13%)中转开腹。产妇的中位年龄为 31 岁(27.8-36 岁),估计的中位孕龄(EGA)为 19.5 周(16.5-23.5 周)。18 例(82%)手术在孕中期进行。9 例(40%)有 2 次或以上因类似表现住院。12 例(54%)为首发病例。手术指征包括 12 例(54%)复发性胆绞痛、5 例(22%)急性胆囊炎和 3 例(14%)胆石性胰腺炎。完成 LC 的中位手术时间为 65 分钟(60-95 分钟)。7 例(32%)进行了术中胆管造影术,其中 5 例(71%)采用了子宫铅屏蔽保护。无胎儿丢失或子宫损伤。完成 LC 的中位住院时间为 3 天(2-7 天)。2 例(10%)完成的 LC 出现严重并发症,需再次手术。5 例(23%)失访。术后至分娩的中位时间为 13 周(11-15 周)。2 例(12%)早产,随后出现新生儿并发症。
产前 LC 效果安全。在怀孕期间,为了治疗有症状的胆石症,可能需要更多地应用 LC。