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腹腔镜胆囊切除术在妊娠中的应用:澳大利亚回顾性队列研究。

Laparoscopic cholecystectomy in pregnancy: An Australian retrospective cohort study.

机构信息

Department of Surgery, Western Health, Footscray, Victoria, Australia.

Department of Surgery, Western Health, Footscray, Victoria, Australia.

出版信息

Int J Surg. 2015 Jun;18:220-3. doi: 10.1016/j.ijsu.2015.05.005. Epub 2015 May 9.

Abstract

INTRODUCTION

Biliary tract disease is a common non-obstetric surgical presentation during pregnancy. Although small international series demonstrate favourable outcomes following laparoscopic cholecystectomy (LC) during pregnancy, there is a paucity of Australian data to complement these findings.

METHOD

Between 1st January 2003 and 30th June 2013, all patients undergoing planned LC during pregnancy at Western Health were retrospectively identified.

RESULTS

Twenty-two patients underwent planned LC with 3 (13%) cases converted to open surgery. The median maternal age was 31 years (27.8-36) with an estimated median gestational age (EGA) of 19.5 weeks (16.5-23.5). Eighteen (82%) cases were performed during the second trimester. Nine (40%) patients had 2 or more hospital admissions for similar presentations. Twelve (54%) were performed as index cases. Operative indications included 12 (54%) with recurrent biliary colic, five (22%) with acute cholecystitis and 3 (14%) with gallstone pancreatitis. Median operating time for completed LCs was 65 min (60-95). Intra-operative cholangiogram was performed in seven (32%) cases, 5 (71%) of which employed protective uterine lead shielding. There was no fetal loss or uterine injury. Median hospital stay was 3 days (2-7) for completed LCs. Major morbidity occurred in 2 (10%) completed LCs that required a return to theatre. Five (23%) births were lost to follow up. The median time to delivery post-surgery was 13 weeks (11-15). Two (12%) preterm deliveries occurred, with subsequent neonatal complications.

CONCLUSION

Antenatal laparoscopic cholecystectomy demonstrated comparably safe outcomes. Increasing its utilization to manage symptomatic cholelithiasis during pregnancy may be considered.

摘要

介绍

胆道疾病是妊娠期常见的非产科外科疾病。尽管国际上有一些小的系列研究表明,在怀孕期间行腹腔镜胆囊切除术(LC)的效果良好,但澳大利亚的数据还不足以补充这些发现。

方法

在 2003 年 1 月 1 日至 2013 年 6 月 30 日期间,回顾性地分析了在 Western Health 行计划性 LC 的所有孕妇病例。

结果

22 例孕妇行计划性 LC,其中 3 例(13%)中转开腹。产妇的中位年龄为 31 岁(27.8-36 岁),估计的中位孕龄(EGA)为 19.5 周(16.5-23.5 周)。18 例(82%)手术在孕中期进行。9 例(40%)有 2 次或以上因类似表现住院。12 例(54%)为首发病例。手术指征包括 12 例(54%)复发性胆绞痛、5 例(22%)急性胆囊炎和 3 例(14%)胆石性胰腺炎。完成 LC 的中位手术时间为 65 分钟(60-95 分钟)。7 例(32%)进行了术中胆管造影术,其中 5 例(71%)采用了子宫铅屏蔽保护。无胎儿丢失或子宫损伤。完成 LC 的中位住院时间为 3 天(2-7 天)。2 例(10%)完成的 LC 出现严重并发症,需再次手术。5 例(23%)失访。术后至分娩的中位时间为 13 周(11-15 周)。2 例(12%)早产,随后出现新生儿并发症。

结论

产前 LC 效果安全。在怀孕期间,为了治疗有症状的胆石症,可能需要更多地应用 LC。

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