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牙齿美白机制综述

Review of the Mechanism of Tooth Whitening.

作者信息

Kwon So Ran, Wertz Philip W

机构信息

Department of Operative Dentistry, University of Iowa College of Dentistry & Dental Clinics, Iowa City, IA, USA.

Oral Pathology, Radiology and Medicine, Dows Institute for Dental Research, University of Iowa College of Dentistry & Dental Clinics, Iowa City, IA, USA.

出版信息

J Esthet Restor Dent. 2015 Sep-Oct;27(5):240-57. doi: 10.1111/jerd.12152. Epub 2015 May 13.

DOI:10.1111/jerd.12152
PMID:25969131
Abstract

PURPOSE

This review integrated the current literature on diffusion of whitening agents, their interactions with stain molecules, and changes to the surface, with the aim of establishing a better understanding of the mechanism underlying tooth whitening.

MATERIALS AND METHODS

An electronic PubMed database search, with combinations of the following terms was performed: Tooth Bleaching, Tooth Bleaching Agent, Hydrogen Peroxide, Pharmacokinetics, Tooth Permeability, Oxidation-Reduction, Tooth Demineralization, and Color.

RESULTS

Tooth whitening is a dynamic process that involves diffusion of the whitening material to interact with stain molecules and also involves micromorphologic alterations on the surface and changes within the tooth that affect its optical properties. The interaction seems not to be limited to stain molecules, but rather an affinity-based interaction process that also accompanies effects on sound enamel and dentin structures.

CONCLUSIONS

This review underlines that supervision by dental health professionals as recommended by the American Dental Association (ADA) Council on Scientific Affairs is critical to achieving a successful and safe whitening outcome.

CLINICAL SIGNIFICANCE

The mechanism that underlies tooth whitening with the use of peroxide-based materials is a complex phenomenon encompassing diffusion, interaction, and surfaces changes within the tooth. Therefore, supervision by dental health professionals as recommended by the ADA Council on Scientific Affairs is imperative to achieve a successful and safe whitening outcome.

摘要

目的

本综述整合了有关美白剂扩散、它们与污渍分子的相互作用以及牙齿表面变化的当前文献,旨在更好地理解牙齿美白的潜在机制。

材料与方法

利用电子PubMed数据库进行检索,检索词组合如下:牙齿漂白、牙齿漂白剂、过氧化氢、药代动力学、牙齿渗透性、氧化还原、牙齿脱矿质和颜色。

结果

牙齿美白是一个动态过程,涉及美白材料的扩散以与污渍分子相互作用,还涉及牙齿表面的微观形态改变以及牙齿内部影响其光学性质的变化。这种相互作用似乎不仅限于污渍分子,而是一个基于亲和力的相互作用过程,同时也伴随着对健康牙釉质和牙本质结构的影响。

结论

本综述强调,按照美国牙科协会(ADA)科学事务委员会的建议,由牙科保健专业人员进行监督对于实现成功且安全的美白效果至关重要。

临床意义

使用基于过氧化物的材料进行牙齿美白的潜在机制是一个复杂的现象,包括扩散、相互作用以及牙齿内部的表面变化。因此,按照ADA科学事务委员会的建议,由牙科保健专业人员进行监督对于实现成功且安全的美白效果必不可少。

相似文献

1
Review of the Mechanism of Tooth Whitening.牙齿美白机制综述
J Esthet Restor Dent. 2015 Sep-Oct;27(5):240-57. doi: 10.1111/jerd.12152. Epub 2015 May 13.
2
Effects of elevated hydrogen peroxide 'strip' bleaching on surface and subsurface enamel including subsurface histomorphology, micro-chemical composition and fluorescence changes.过氧化氢“条带”漂白浓度升高对釉质表面和亚表面的影响,包括亚表面组织形态学、微观化学成分及荧光变化。
J Dent. 2007 Jun;35(6):457-66. doi: 10.1016/j.jdent.2007.01.004. Epub 2007 Mar 6.
3
Effects of tooth-whitening gels on enamel and dentin ultrastructure--a confocal laser scanning microscopy pilot study.牙齿美白凝胶对牙釉质和牙本质超微结构的影响——一项共聚焦激光扫描显微镜初步研究。
Compend Contin Educ Dent Suppl. 2000(29):S29-34; quiz S43.
4
Effects of hydrogen peroxide bleaching strips on tooth surface color, surface microhardness, surface and subsurface ultrastructure, and microchemical (Raman spectroscopic) composition.过氧化氢漂白条对牙齿表面颜色、表面显微硬度、表面及亚表面超微结构以及微化学(拉曼光谱)组成的影响。
J Clin Dent. 2006;17(3):72-8.
5
Safety issues of tooth whitening using peroxide-based materials.使用过氧化物基材料进行牙齿美白的安全问题。
Br Dent J. 2013 Jul;215(1):29-34. doi: 10.1038/sj.bdj.2013.629.
6
Micro-structural integrity of dental enamel subjected to two tooth whitening regimes.两种牙齿美白方案对牙釉质微观结构完整性的影响。
Arch Oral Biol. 2010 Apr;55(4):300-8. doi: 10.1016/j.archoralbio.2010.02.009. Epub 2010 Mar 24.
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The bleaching of teeth: a review of the literature.牙齿美白:文献综述
J Dent. 2006 Aug;34(7):412-9. doi: 10.1016/j.jdent.2006.02.002. Epub 2006 Mar 29.
8
In vitro tooth whitening by a sodium bicarbonate/peroxide dentifrice.用碳酸氢钠/过氧化物牙膏进行体外牙齿美白。
J Clin Dent. 1998;9(1):16-21.
9
The art and science of tooth whitening.牙齿美白的艺术与科学。
J Mass Dent Soc. 2005 Winter;53(4):34-7.
10
Effectiveness of a new dentifrice with baking soda and peroxide in removing extrinsic stain and whitening teeth.一种含小苏打和过氧化物的新型牙膏在去除外源性色斑和美白牙齿方面的有效性。
J Clin Dent. 2012;23(3):86-91.

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Dent J (Basel). 2025 Aug 6;13(8):357. doi: 10.3390/dj13080357.
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Bleaching with biocatalysts and violet LED: a randomized clinical trial using a hybrid design with parallel-group and split-mouth approaches : Violet LED and biocatalysts in in-office whitening: a split-mouth trial.生物催化剂与紫光发光二极管美白:采用平行组和分口设计的混合设计的随机临床试验:紫光发光二极管和生物催化剂用于诊室美白:一项分口试验。
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Effect of Blue Covarine Toothpastes on Tooth Colour: A Randomised Crossover Study.
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Int Dent J. 2025 Aug 19;75(5):100938. doi: 10.1016/j.identj.2025.100938.
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Impact of bleaching on white spot lesions: hydrogen peroxide permeability and color alteration.漂白对白斑病变的影响:过氧化氢渗透性和颜色改变。
Clin Oral Investig. 2025 Aug 9;29(9):401. doi: 10.1007/s00784-025-06490-3.
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Effect of Bleaching Agents on the Bond Strength of Orthodontic Brackets.漂白剂对正畸托槽粘结强度的影响。
J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1577-S1579. doi: 10.4103/jpbs.jpbs_147_25. Epub 2025 Jun 18.
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Bleaching at acidic and basic pH for enamel and dentin whitening using internal and external techniques.使用内部和外部技术在酸性和碱性pH值下对牙釉质和牙本质进行漂白以实现美白。
Braz Oral Res. 2025 Jul 7;39:e073. doi: 10.1590/1807-3107bor-2025.vol39.073. eCollection 2025.
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Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding.热带杏仁抗氧化凝胶可减轻强美白剂对即时粘接的不利影响。
Braz Oral Res. 2025 Jul 7;39:e072. doi: 10.1590/1807-3107bor-2025.vol39.072. eCollection 2025.
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[Evaluation of the change in luminosity and sensitivity in laser-assisted teeth whitening: a randomized controlled clinical trial].[激光辅助牙齿美白中亮度和敏感度变化的评估:一项随机对照临床试验]
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Dent J (Basel). 2025 May 19;13(5):216. doi: 10.3390/dj13050216.