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类风湿关节炎草药治疗后的肾上腺抑制。

Adrenal suppression following herbal remedy for rheumatoid arthritis.

作者信息

Premkumar Balasekar, Murthy Muppavarapu Srinivasa, Rajagopal Karuppasamy, Nagaprabu Vadivelmurugan Nagasubramani, Ponugupati Sree Madhuri

机构信息

Department of Pharmacology, PSG College of Pharmacy, Coimbatore, Tamil Nadu, India.

Department of Pharmaceutical Chemistry, Vignan Institute of Pharmaceutical Sciences, Andhra Pradesh, India.

出版信息

J Pharmacol Pharmacother. 2015 Apr-Jun;6(2):110-3. doi: 10.4103/0976-500X.155493.

DOI:10.4103/0976-500X.155493
PMID:25969663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4419244/
Abstract

A patient suffering from rheumatoid arthritis who had extreme adrenal suppression as a result of chronic use of herbal medicines presented with complications of adrenal suppression such as muscle weakness. He also had psychiatric disturbances such as confusion and suicidal tendency. Steroids in the herbal medication were found and hence there exists a need for investigation into their safety and efficacy.

摘要

一名患有类风湿性关节炎的患者因长期使用草药导致肾上腺极度抑制,出现了肾上腺抑制的并发症,如肌肉无力。他还出现了精神障碍,如意识混乱和自杀倾向。在草药中发现了类固醇成分,因此有必要对其安全性和有效性进行调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a97/4419244/2b036b09eae7/JPP-6-110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a97/4419244/1690bbc11c8c/JPP-6-110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a97/4419244/2b036b09eae7/JPP-6-110-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a97/4419244/1690bbc11c8c/JPP-6-110-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a97/4419244/2b036b09eae7/JPP-6-110-g002.jpg

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A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy.系统皮质类固醇治疗并发症的监测和管理实用指南。
Allergy Asthma Clin Immunol. 2013 Aug 15;9(1):30. doi: 10.1186/1710-1492-9-30.
3
Assessment of use of complementary alternative medicine and its impact on quality of life in the patients attending rheumatology clinic, in a tertiary care centre in India.
急性肾上腺功能衰竭:一种掺假草药疗法的潜在致命后果。
BMJ Case Rep. 2019 Feb 19;12(2):e228443. doi: 10.1136/bcr-2018-228443.
4
It is Time to Carpe Diem with Porcine ACTH - A Comparison of Porcine Sequence Corticotropin to Tetracosactide Hexaacetate in Testing the Hypothalamic Pituitary Adrenal Axis in Healthy Individuals.是时候把握猪促肾上腺皮质激素的机遇了——猪序列促肾上腺皮质激素与醋酸二十四肽促皮质素在检测健康个体下丘脑-垂体-肾上腺轴中的比较。
Indian J Endocrinol Metab. 2018 Sep-Oct;22(5):636-640. doi: 10.4103/ijem.IJEM_114_18.
印度一家三级护理中心对风湿科门诊患者补充替代医学的使用情况及其对生活质量影响的评估。
Indian J Med Sci. 2011 Feb;65(2):50-7.
4
Complementary and alternative medicine use in rheumatoid arthritis: an audit of patients visiting a tertiary care centre.类风湿关节炎患者使用补充和替代医学的情况:对一家三级医疗中心就诊患者的审计
Natl Med J India. 2007 Sep-Oct;20(5):236-9.
5
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