Wiener R Constance, Wiener Michael A, McNeil Daniel W
Dental Practice and Rural Health, School of Dentistry, West Virginia University, Morgantown, WV, USA.
Department of Epidemiology, School of Public Health, West Virginia University, Morgantown, WV, USA.
Community Dent Oral Epidemiol. 2015 Oct;43(5):433-43. doi: 10.1111/cdoe.12168. Epub 2015 May 13.
The purpose of this study was to examine the association between participants (i) who reported having had clinical diagnoses of depression and anxiety with 6+ teeth removed and (ii) who reported having had clinical diagnoses of depression and anxiety with edentulism.
The Behavioral Risk Factor Surveillance System (BRFSS) Survey 2010 was used for the study. Analyses involved using SAS 9.3® to determine variable frequencies, Rao-Scott chi-square bivariate analyses, and Proc Surveylogistic for the logistic regressions on complex survey designs. Participants eligibility included being 18 years or older and having complete data on depression, anxiety, and number of teeth removed.
There were 76 292 eligible participants; 13.4% reported an anxiety diagnosis, 16.7% reported a depression diagnosis, and 8.6% reported comorbid depression and anxiety. The adjusted logistic regression models were significant for anxiety and depression alone and in combination for 6+ teeth removed (AOR: anxiety 1.23; 95% CI: 1.10, 1.38; P = 0.0773; AOR: depression 1.23; 95% CI: 1.10, 1.37; P = 0.0275; P < 0.0001; and AOR: comorbid depression and anxiety 1.30; 95% CI: 1.14, 1.49; P = 0.0001). However, the adjusted models with edentulism as the outcome failed to reach significance.
Comorbid depression and anxiety are associated independently with 6+ teeth removed compared with 0-5 teeth removed in a national study conducted in United States. Comorbid depression and anxiety were not shown to be associated with edentulism as compared with any teeth present.
本研究旨在探讨以下两类参与者之间的关联：（i）报告有抑郁症和焦虑症临床诊断且拔除6颗及以上牙齿的参与者；（ii）报告有抑郁症和焦虑症临床诊断且无牙的参与者。
本研究使用了2010年行为危险因素监测系统（BRFSS）调查。分析包括使用SAS 9.3®确定变量频率、Rao-Scott卡方双变量分析以及用于复杂调查设计逻辑回归的Proc Surveylogistic过程。参与者资格包括年龄在18岁及以上，且有关于抑郁症、焦虑症和拔牙数量的完整数据。
共有76292名符合条件的参与者；13.4%报告有焦虑症诊断，16.7%报告有抑郁症诊断，8.6%报告有抑郁症和焦虑症共病。调整后的逻辑回归模型对于单独的焦虑症和抑郁症以及拔除6颗及以上牙齿的合并情况均具有显著性（比值比：焦虑症1.23；95%置信区间：1.10，1.38；P = 0.0773；比值比：抑郁症1.23；95%置信区间：1.10，1.37；P = 0.0275；P < 0.0001；比值比：抑郁症和焦虑症共病1.30；95%置信区间：1.14，1.49；P = 0.0001）。然而，以无牙为结果的调整模型未达到显著性。
在美国进行的一项全国性研究中，与拔除0 - 5颗牙齿相比，抑郁症和焦虑症共病与拔除6颗及以上牙齿独立相关。与有牙情况相比，未显示抑郁症和焦虑症共病与无牙有关。
