• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Measurement of regional cerebral blood flow and accentuation of the primary auditory cortex with single photon emission computed tomography.

作者信息

Schadel A, Fischer M

机构信息

HNO-Klinik am Klinikum Mannheim, Universität Heidelberg, Federal Republic of Germany.

出版信息

Arch Otorhinolaryngol. 1989;246(4):205-9. doi: 10.1007/BF00453663.

DOI:10.1007/BF00453663
PMID:2597080
Abstract

Conventional brain scanning uses polar tracers which do not penetrate the normal blood-brain barrier. Radiolabeled amines like 123-iodoamphetamine (IMP) cross the barrier to inhibit serotonin and norepinephrine in synaptosomes. Studies of cerebral perfusion and function seem to be successful with such labeling. We advance the hypothesis for an increased IMP uptake in the stimulated primary auditory cortex. The method of single photon emission computed tomography (SPECT) is described. We have also been able to demonstrate marking of the primary auditory cortex by an increased amphetamine input in 6 out of 15 cases during stimulation by white noise.

摘要

相似文献

1
Measurement of regional cerebral blood flow and accentuation of the primary auditory cortex with single photon emission computed tomography.
Arch Otorhinolaryngol. 1989;246(4):205-9. doi: 10.1007/BF00453663.
2
Semiquantitative analyses of dynamic single photon emission computed tomography (SPECT) of the primary auditory cortex.
Arch Otorhinolaryngol. 1989;246(3):151-5. doi: 10.1007/BF00456657.
3
Spect-studies of the brain with stimulation of the auditory cortex.通过刺激听觉皮层对大脑进行单光子发射计算机断层扫描研究。
Scand Audiol Suppl. 1988;30:177-80.
4
[Quantitation of regional cerebral blood flow using 123I-IMP from a single SPECT scan and a single blood sampling--analysis on statistical error source and optimal scan time].[利用单次SPECT扫描和单次采血，通过123I-IMP定量分析局部脑血流量——统计误差源及最佳扫描时间分析]
Kaku Igaku. 1995 Mar;32(3):263-70.
5
A comparative cerebral blood flow study in a baboon model with acetazolamide provocation: 99mTc-HMPAO vs 123I(IMP).在乙酰唑胺激发的狒狒模型中进行的脑血流比较研究：99mTc-HMPAO 与 123I(IMP)对比
Nucl Med Biol. 1995 Apr;22(3):373-8. doi: 10.1016/0969-8051(94)00094-z.
6
Brain imaging with emission computed tomography and radiolabeled amines.
Invest Radiol. 1982 May-Jun;17(3):206-15.
7
Regional dynamics of N-isopropyl-(123I)p-iodoamphetamine in human brain.
J Nucl Med. 1989 Feb;30(2):150-6.
8
Theoretical and experimental assessment of the kinetic properties of N-isopropyl-p-[123I]iodoamphetamine in the human brain.N-异丙基-p-[123I]碘安非他明在人脑中动力学特性的理论与实验评估。
Neurol Med Chir (Tokyo). 1993 Dec;33(12):809-14. doi: 10.2176/nmc.33.809.
9
[Abnormally distributed regional cerebral blood flow in brain malformations detected by single photon emission computed tomography].[单光子发射计算机断层扫描检测脑畸形中区域脑血流分布异常]
Rinsho Shinkeigaku. 1997 Feb;37(2):99-105.
10
[A non-invasive quantitative measurement of cerebral blood flow using N-isopropyl-[123I]p-iodoamphetamine and single photon emission CT].使用 N-异丙基-[123I]对碘安非他明和单光子发射计算机断层扫描进行脑血流的无创定量测量
Kaku Igaku. 1991 Sep;28(9):1013-9.

本文引用的文献

1
A refined method to relate morphological and functional aspects of aphasia.一种关联失语症形态学和功能方面的精细方法。
Eur Neurol. 1981;20(2):69-79. doi: 10.1159/000115210.
2
Comparison of N-isopropyl (I-123) p-iodoamphetamine brain scans using Anger camera scintigraphy and single-photon emission tomography.使用安格相机闪烁扫描法和单光子发射断层扫描法对 N-异丙基（I-123）对碘安非他明脑部扫描结果的比较。
Radiology. 1982 Dec;145(3):789-93. doi: 10.1148/radiology.145.3.6983088.
3
Initial experience with SPECT (single-photon computerized tomography) of the brain using N-isopropyl I-123 p-iodoamphetamine: concise communication.
J Nucl Med. 1982 Mar;23(3):191-5.
4
Noninvasive tomographic study of cerebral blood flow and oxygen metabolism in vivo. Potentials, limitations, and clinical applications in cerebral ischemic disorders.活体脑血流和氧代谢的无创断层研究。在脑缺血性疾病中的潜力、局限性及临床应用。
Eur Neurol. 1981;20(3):273-84. doi: 10.1159/000115247.
5
Regional cerebral blood flow in stroke by 133Xenon inhalation and emission tomography.
Stroke. 1981 May-Jun;12(3):284-8. doi: 10.1161/01.str.12.3.284.
6
Brain imaging with emission computed tomography and radiolabeled amines.
Invest Radiol. 1982 May-Jun;17(3):206-15.
7
Quantifying local cerebral blood flow by N-isopropyl-p-[123I]iodoamphetamine (IMP) tomography.通过 N-异丙基-p-[123I]碘安非他明（IMP）断层扫描定量局部脑血流量。
J Nucl Med. 1982 Mar;23(3):196-203.
8
N-isopropyl-[123I] p-iodoamphetamine: single-pass brain uptake and washout; binding to brain synaptosomes; and localization in dog and monkey brain.N-异丙基-[123I]对碘安非他明：单次通过脑摄取与清除；与脑突触体的结合；以及在犬和猴脑中的定位。
J Nucl Med. 1980 Oct;21(10):947-52.
9
[Cerebral emission computer tomography (SPECT) with 123I-labeled amphetamines].
Dtsch Med Wochenschr. 1984 Jul 27;109(30):1155-9. doi: 10.1055/s-2008-1069340.
10
[Comparison of 133xenon and 123I-isopropylamphetamine for measuring regional cerebral circulation].[用于测量局部脑循环的133氙与123I-异丙基安非他明的比较]
Rofo. 1984 Aug;141(2):212-9. doi: 10.1055/s-2008-1053119.