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用于无损离子操控的结构中的离子捕获、存储和喷射

Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations.

作者信息

Zhang Xinyu, Garimella Sandilya V B, Prost Spencer A, Webb Ian K, Chen Tsung-Chi, Tang Keqi, Tolmachev Aleksey V, Norheim Randolph V, Baker Erin S, Anderson Gordon A, Ibrahim Yehia M, Smith Richard D

机构信息

Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States.

出版信息

Anal Chem. 2015 Jun 16;87(12):6010-6. doi: 10.1021/acs.analchem.5b00214. Epub 2015 May 26.

Abstract

A new Structures for Lossless Ion Manipulations (SLIM) module, having electrode arrays patterned on a pair of parallel printed circuit boards (PCB), was constructed and utilized to investigate capabilities for ion trapping at a pressure of 4 Torr. Positive ions were confined by application of RF voltages to a series of inner rung electrodes with alternating phase on adjacent electrodes, in conjunction with positive DC potentials on surrounding guard electrodes on each PCB. An axial DC field was also introduced by stepwise varying the DC potentials applied to the inner rung electrodes to control the ion transport and accumulation inside the ion trapping region. We show that ions can be trapped and accumulated with up to 100% efficiency, stored for at least 5 h with no significant losses, and then could be rapidly ejected from the SLIM trap. The present results provide a foundation for the development of much more complex SLIM devices that facilitate extended ion manipulations.

摘要

构建了一种新型无损离子操纵(SLIM)模块,其电极阵列图案化在一对平行印刷电路板(PCB)上,并用于研究在4托压力下的离子捕获能力。通过向一系列内圈电极施加射频电压,并在相邻电极上施加交替相位,同时在每个PCB上的周围保护电极上施加正直流电势,来限制正离子。还通过逐步改变施加到内圈电极的直流电势来引入轴向直流电场,以控制离子在离子捕获区域内的传输和积累。我们表明,离子可以以高达100%的效率被捕获和积累,存储至少5小时且无明显损失,然后可以从SLIM阱中快速弹出。目前的结果为开发更复杂的SLIM装置奠定了基础,这些装置有助于扩展离子操纵。

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本文引用的文献

1
Development of a New Ion Mobility (Quadrupole) Time-of-Flight Mass Spectrometer.
Int J Mass Spectrom. 2015 Feb 1;377:655-662. doi: 10.1016/j.ijms.2014.07.034.
2
Simulation of electric potentials and ion motion in planar electrode structures for lossless ion manipulations (SLIM).
J Am Soc Mass Spectrom. 2014 Nov;25(11):1890-6. doi: 10.1007/s13361-014-0976-y. Epub 2014 Sep 26.
4
Characterization of ion dynamics in structures for lossless ion manipulations.
Anal Chem. 2014 Sep 16;86(18):9162-8. doi: 10.1021/ac502054p. Epub 2014 Sep 4.
6
Collisional focusing effects in radio frequency quadrupoles.
J Am Soc Mass Spectrom. 1992 May;3(4):398-408. doi: 10.1016/1044-0305(92)87067-9.
7
Penning traps with unitary architecture for storage of highly charged ions.
Rev Sci Instrum. 2012 Feb;83(2):023103. doi: 10.1063/1.3685246.
8
Nondestructive ion trap mass analysis at high pressure.
Anal Chem. 2011 Feb 1;83(3):685-9. doi: 10.1021/ac1027808. Epub 2010 Dec 20.
9
Ion trap mass analysis at high pressure: an experimental characterization.
J Mass Spectrom. 2010 Jan;45(1):26-34. doi: 10.1002/jms.1684.
10
Automated gain control ion funnel trap for orthogonal time-of-flight mass spectrometry.
Anal Chem. 2008 Jul 15;80(14):5367-76. doi: 10.1021/ac8003488. Epub 2008 May 31.

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