Berger Gidon, Bitterman Roni, Azzam Zaher S
Department of Internal Medicine B, Rambam Health Care Campus, Haifa, Israel;
Department of Internal Medicine B, Rambam Health Care Campus, Haifa, Israel; ; Ruth & Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.
Rambam Maimonides Med J. 2015 Apr 29;6(2):e0018. doi: 10.5041/RMMJ.10202. eCollection 2015 Apr.
The human body hosts rich and diverse microbial communities. Our microbiota affects the normal human physiology, and compositional changes might alter host homeostasis and, therefore, disease risk. The microbial community structure may sometimes occupy discrete configurations and under certain circumstances vary continuously. The ability to characterize accurately the ecology of human-associated microbial communities became possible by advances in deep sequencing and bioinformatics analyses.
人体承载着丰富多样的微生物群落。我们的微生物群影响着人类的正常生理功能,其组成变化可能会改变宿主的内环境稳定,进而影响疾病风险。微生物群落结构有时可能呈现离散状态,在某些情况下也会持续变化。深度测序和生物信息学分析技术的进步,使准确描述与人类相关的微生物群落生态成为可能。