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本文引用的文献

1
Analyses of the stability and core taxonomic memberships of the human microbiome.人类微生物组的稳定性和核心分类群分析。
PLoS One. 2013 May 6;8(5):e63139. doi: 10.1371/journal.pone.0063139. Print 2013.
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Duodenal infusion of donor feces for recurrent Clostridium difficile.经十二指肠输注供体粪便治疗复发性艰难梭菌感染。
N Engl J Med. 2013 Jan 31;368(5):407-15. doi: 10.1056/NEJMoa1205037. Epub 2013 Jan 16.
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Genomic approaches to studying the human microbiota.基于基因组学的方法研究人类微生物组。
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Novel bacterial taxa in the human microbiome.人类微生物组中的新型细菌分类群。
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Structure, function and diversity of the healthy human microbiome.健康人体微生物组的结构、功能与多样性。
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6
Role of the microbiota in inflammatory bowel diseases.肠道微生物群在炎症性肠病中的作用。
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7
Disordered microbial communities in the upper respiratory tract of cigarette smokers.吸烟人群上呼吸道中紊乱的微生物群落。
PLoS One. 2010 Dec 20;5(12):e15216. doi: 10.1371/journal.pone.0015216.
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Vaginal microbiome of reproductive-age women.育龄期女性的阴道微生物组。
Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1(Suppl 1):4680-7. doi: 10.1073/pnas.1002611107. Epub 2010 Jun 3.
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Disordered microbial communities in asthmatic airways.哮喘气道中的失调微生物群落。
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What are the consequences of the disappearing human microbiota?人类微生物组消失会带来什么后果?
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人类微生物群:一个“帝国”的崛起。

The human microbiota: the rise of an "empire".

作者信息

Berger Gidon, Bitterman Roni, Azzam Zaher S

机构信息

Department of Internal Medicine B, Rambam Health Care Campus, Haifa, Israel;

Department of Internal Medicine B, Rambam Health Care Campus, Haifa, Israel; ; Ruth & Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.

出版信息

Rambam Maimonides Med J. 2015 Apr 29;6(2):e0018. doi: 10.5041/RMMJ.10202. eCollection 2015 Apr.

DOI:10.5041/RMMJ.10202
PMID:25973270
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4422457/
Abstract

The human body hosts rich and diverse microbial communities. Our microbiota affects the normal human physiology, and compositional changes might alter host homeostasis and, therefore, disease risk. The microbial community structure may sometimes occupy discrete configurations and under certain circumstances vary continuously. The ability to characterize accurately the ecology of human-associated microbial communities became possible by advances in deep sequencing and bioinformatics analyses.

摘要

人体承载着丰富多样的微生物群落。我们的微生物群影响着人类的正常生理功能,其组成变化可能会改变宿主的内环境稳定,进而影响疾病风险。微生物群落结构有时可能呈现离散状态,在某些情况下也会持续变化。深度测序和生物信息学分析技术的进步,使准确描述与人类相关的微生物群落生态成为可能。