Sharma Kirti, Behera Joshil Kumar, Kumar Naresh, Sood Sushma, Madan Harnam Singh, Das Sibadatta
Department of Physiology, Shaheed Hasan Khan Mewati (SHKM) Government Medical College, Nalhar, Uttarkhand, India.
Department of Physiology, Government Medical College (GMC), Srinagar, Pauri Garhwal, India.
N Am J Med Sci. 2015 Apr;7(4):131-4. doi: 10.4103/1947-2714.156006.
Hypothyroidism is known to be associated with impairment of hearing. The hearing impairment may be conductive, sensorineural, or mixed.
The aim is to assess the auditory pathway by brainstem auditory evoked potentials (BAEPs) in newly diagnosed patients of subclinical hypothyroidism and healthy sex- and age-matched controls.
The study included 25 healthy sex- and age-matched controls (Group I) and 25 patients of newly diagnosed subclinical hypothyroidism (Group II). The recording was taken by using RMS EMG EP MK2 equipment. The unpaired Student's t-test was used and a P value <0.05 was considered significant.
Wave V of right ear BAEP in group II was prolonged (6 ± 0.62 ms) compared to group I (5.49 ± 0.26 ms), and wave V of left ear BAEP in group II was prolonged (5.84 ± 0.57 ms) compared to group I (5.47 ± 0.35 ms). There was no significant coefficient of correlation between wave V and inter-peak latency (IPL) I-V compared to thyroid-stimulating hormone (TSH) levels of both the ears.
The prolongation of wave V in BAEPs of both ears suggests that the central auditory pathway is affected significantly in subclinical hypothyroid patients.
已知甲状腺功能减退与听力损害有关。听力损害可能是传导性、感音神经性或混合性的。
旨在通过脑干听觉诱发电位（BAEP）评估新诊断的亚临床甲状腺功能减退患者及年龄和性别匹配的健康对照者的听觉通路。
该研究纳入了25名年龄和性别匹配的健康对照者（I组）和25名新诊断的亚临床甲状腺功能减退患者（II组）。使用RMS EMG EP MK2设备进行记录。采用非配对学生t检验，P值<0.05被认为具有统计学意义。
与I组（5.49±0.26毫秒）相比，II组右耳BAEP的V波延长（6±0.62毫秒），与I组（5.47±0.35毫秒）相比，II组左耳BAEP的V波延长（5.84±0.57毫秒）。与双耳的促甲状腺激素（TSH）水平相比，V波与峰间潜伏期（IPL）I-V之间无显著相关性。
双耳BAEP中V波延长表明亚临床甲状腺功能减退患者的中枢听觉通路受到显著影响。
