James Paget University Hospitals NHS Foundation Trust, Norfolk, UK.
Clin Otolaryngol. 2012 Feb;37(1):23-7. doi: 10.1111/j.1749-4486.2012.02431.x.
The 'Sniffin' Sticks' olfactory test contains pen-like odour dispensing devices which are used to assess olfactory threshold, discrimination and identification. Odour identification is strongly dependent on familiarity with the odours and has an important cultural component which has limited the usefulness of other validated tests. The 'Sniffin' Sticks' test was developed in Germany and is validated in other countries but not in the UK. This study aims to validate the applicability of 'Sniffin' Sticks' in a local population.
Prospective controlled study.
Rhinology or olfactory disorder clinic.
About 82 subjects, 33 healthy volunteers with a reported normal sense of smell, and 49 patients with an impaired sense of smell presenting either at a rhinology or an olfactory disorder clinic. Each subject's olfactory function was assessed using the 'Sniffin' Sticks' test with a maximum score of 48.
Threshold, discrimination and identification scores along with the combined olfactory score.
The mean age of the subjects tested was 46.7 years; 46 female and 36 male. In the patient group 36 were hyposmic and 13 anosmic. In the healthy volunteers group all subjects were normosmic. In the control group the mean combined olfactory score was 34.5 (±2.5). The mean combined score in the patients group was 20.8 (±7.4). Odour threshold scores were 3.7(±2.8) for patients (hyposmics and anomics) and 8.3(±1.8) for controls. In the identification test the controls mean score was 13.6 (±1.2) for while the patients' mean score was 8.6 (±3.5).
In our sample of the local population the combined olfactory and odour identification scores for healthy volunteers and patients with olfactory disorders are comparable with the normative data published on large samples of European populations. However, modification of a few of the distracters is recommended for British patients based on our findings.
“Sniffin' Sticks”嗅觉测试包含类似钢笔的气味分配设备,用于评估嗅觉阈值、辨别和识别。气味识别强烈依赖于对气味的熟悉程度,并且具有重要的文化组成部分,这限制了其他经过验证的测试的实用性。“Sniffin' Sticks”测试在德国开发,并在其他国家得到验证,但在英国没有得到验证。本研究旨在验证该测试在当地人群中的适用性。
前瞻性对照研究。
鼻科学或嗅觉障碍诊所。
约 82 名受试者,33 名嗅觉正常的健康志愿者和 49 名嗅觉障碍患者,分别在鼻科学或嗅觉障碍诊所就诊。每位受试者的嗅觉功能均使用“Sniffin' Sticks”测试进行评估,最高得分为 48 分。
阈值、辨别和识别分数以及综合嗅觉评分。
测试对象的平均年龄为 46.7 岁;女性 46 名,男性 36 名。在患者组中,36 名患者为嗅觉减退,13 名患者为嗅觉丧失。在健康志愿者组中,所有受试者均为嗅觉正常。在对照组中,平均综合嗅觉评分为 34.5(±2.5)。患者组的平均综合评分是 20.8(±7.4)。患者(嗅觉减退和嗅觉丧失)的气味阈值评分为 3.7(±2.8),对照组为 8.3(±1.8)。在识别测试中,对照组的平均得分为 13.6(±1.2),而患者组的平均得分为 8.6(±3.5)。
在我们的当地人群样本中,健康志愿者和嗅觉障碍患者的综合嗅觉和气味识别评分与在欧洲大样本中发表的规范数据相当。然而,根据我们的发现,建议对英国患者修改一些干扰项。