Porela-Tiihonen Susanna, Roine Risto P, Sintonen Harri, Kaarniranta Kai, Kokki Merja, Kokki Hannu
Department of Anaesthesia and Operative Services, Kuopio University Hospital, Kuopio, Finland.
Department of Anaesthesiology and Intensive Care, School of Medicine, University of Eastern Finland, Kuopio, Finland.
Acta Ophthalmol. 2016 Feb;94(1):21-5. doi: 10.1111/aos.12755. Epub 2015 May 14.
Disease-specific instruments have shown significant gains in measuring health-related quality of life (HRQoL) in subjects having cataract surgery. However, the usage of generic instruments has resulted in conflicting evidence.
In this prospective study, we have evaluated the impact of cataract surgery on subjects' HRQoL measured with a 15-dimension generic instrument, the 15D. The HRQoL of cataract subjects was compared with that of an age- and gender-standardized sample of the general population in Finland. A total of 152 subjects (mean age 74 years, 66% females) with a first-eye cataract surgery completed the 15D questionnaire both before and 12 months after cataract surgery.
When compared with the general population, cataract subjects had much lower HRQoL at baseline (mean difference 0.037 (95% CI: 0.020, 0.054), p < 0.001). At 12 months after cataract surgery, the overall utility index improved from the mean of 0.837 to 0.855 (mean difference 0.018 (95% CI: 0.007, 0.029), p = 0.002). Significant improvement was observed on the following five dimensions: seeing, moving, hearing, usual activities and discomfort/symptoms in the 15D questionnaire.
Our data indicate that at 12 months after first-eye cataract surgery, patients' HRQoL is slightly better than that before surgery. However, patients' postoperative HRQoL may remain lower than that of an age-and gender-standardized control population.
特定疾病工具在测量白内障手术患者的健康相关生活质量（HRQoL）方面已显示出显著成效。然而，通用工具的使用却产生了相互矛盾的证据。
在这项前瞻性研究中，我们评估了白内障手术对使用15维度通用工具15D测量的患者HRQoL的影响。将白内障患者的HRQoL与芬兰一般人群的年龄和性别标准化样本进行比较。共有152名接受第一眼白内障手术的患者（平均年龄74岁，66%为女性）在白内障手术前和术后12个月完成了15D问卷。
与一般人群相比，白内障患者在基线时的HRQoL要低得多（平均差异0.037（95%CI：0.020，0.054），p<0.001）。白内障手术后12个月，总体效用指数从平均0.837提高到0.855（平均差异0.018（95%CI：0.007，0.029），p = 0.002）。在15D问卷的以下五个维度上观察到显著改善：视力、活动能力、听力、日常活动以及不适/症状。
我们的数据表明，第一眼白内障手术后12个月，患者的HRQoL略优于手术前。然而，患者术后的HRQoL可能仍低于年龄和性别标准化的对照人群。
