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白内障手术对单眼患者视力相关生活质量及心理困扰的影响。

The Impact of Cataract Surgery on Vision-Related Quality of Life and Psychological Distress in Monocular Patients.

作者信息

Li Xuepei, Lin Jianqiang, Chen Zidong, Jin Guangming, Zheng Danying

机构信息

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

出版信息

J Ophthalmol. 2021 Dec 21;2021:4694577. doi: 10.1155/2021/4694577. eCollection 2021.

Abstract

PURPOSE

To determine the changes in vision-related quality of life and psychological distress after cataract surgery in monocular patients and to compared these with a control group of age- and gender-matched binocular patients.

METHODS

We enrolled 40 monocular patients and 40 binocular patients who underwent cataract surgery from August 2017 to December 2018. All participants undertook eye examinations and answered questionnaires (the National Eye Institute Visual Function Questionnaire, Self-rating Anxiety Scale, and Self-rating Depression Scale) before and after cataract surgery.

RESULT

The monocular patients had significantly worse mean CDVA than the binocular patients before and after surgery. However, there was no significant difference between the increases gained by the two groups. Mean composite VFQ-25 scores of the monocular group were significantly lower than those of the binocular group before and after surgery, but the improvement experienced by the monocular group was statistically larger than the binocular group (37.20 ± 12.84 vs. 19.11 ± 5.13, < 0.001). Mean standard SAS scores of monocular patients were significantly higher than those of binocular controls before and after surgery, while monocular patients experienced a significant greater decline of SAS scores (-9.41 ± 5.39 VS -3.84 ± 1.61, < 0.001). Mean standard SDS scores of the monocular group were significantly higher than those of the control group before and after surgery, but the monocular group experienced a significantly greater decline of SDS scores following cataract surgery (-11.91 ± 6.38 VS -4.78 ± 1.79, < 0.001). There was a significant correlation between the preoperative logMAR CDVA and both the postoperative logMAR CDVA ( = 0.63, < 0.001) and the changes in the logMAR CDVA ( = -0.881, < 0.001) for monocular patients. Linear regression analyses suggested that higher postoperative VFQ-25 scores had significant associations with better preoperative CDVA and the absence of systemic comorbidity (both < 0.05). Age and ocular comorbidity were significantly associated with postoperative SAS scores (both < 0.05). Age and systemic comorbidity remained significant impact factors for SDS scores (both < 0.05).

CONCLUSION

Monocular patients reported greater improvement in vision-related quality of life and greater decline in the level of anxiety and depression than binocular control subjects, despite having similar CDVA gains after cataract surgery. We argue that it is not a better choice for monocular patients to delay cataract surgery until the cataract is very advanced. A clear understanding of the impact of cataract surgery on vision-related quality of life and psychological distress in monocular patients is needed by ophthalmologists when making surgery decision.

摘要

目的

确定单眼患者白内障手术后视力相关生活质量和心理困扰的变化,并与年龄和性别匹配的双眼患者对照组进行比较。

方法

我们纳入了2017年8月至2018年12月期间接受白内障手术的40名单眼患者和40名双眼患者。所有参与者在白内障手术前后均进行了眼部检查并回答了问卷(美国国立眼科研究所视觉功能问卷、自评焦虑量表和自评抑郁量表)。

结果

单眼患者术前和术后的平均矫正视力(CDVA)均显著低于双眼患者。然而,两组的视力提高幅度没有显著差异。单眼组术前和术后的平均综合视觉功能问卷-25(VFQ-25)得分均显著低于双眼组,但单眼组的改善在统计学上大于双眼组(37.20±12.84 vs. 19.11±5.13,P<0.001)。单眼患者术前和术后的平均标准焦虑自评量表(SAS)得分均显著高于双眼对照组,而单眼患者的SAS得分下降幅度显著更大(-9.41±5.39 VS -3.84±1.61,P<0.001)。单眼组术前和术后的平均标准抑郁自评量表(SDS)得分均显著高于对照组,但单眼组白内障手术后的SDS得分下降幅度显著更大(-11.91±6.38 VS -4.78±1.79,P<0.001)。单眼患者术前的最小分辨角对数(logMAR)CDVA与术后logMAR CDVA(r=0.63,P<0.001)以及logMAR CDVA的变化(r=-0.881,P<0.001)之间均存在显著相关性。线性回归分析表明,术后较高的VFQ-25得分与较好的术前CDVA以及无全身合并症显著相关(均P<0.05)。年龄和眼部合并症与术后SAS得分显著相关(均P<0.05)。年龄和全身合并症仍然是SDS得分的显著影响因素(均P<"0.05)。

结论

尽管单眼患者白内障手术后的CDVA改善情况与双眼对照组相似,但他们报告的视力相关生活质量改善更大,焦虑和抑郁水平下降更大。我们认为,对于单眼患者来说,将白内障手术推迟到白内障非常严重时并不是一个更好的选择。眼科医生在做出手术决策时,需要清楚了解白内障手术对单眼患者视力相关生活质量和心理困扰的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a071/8714322/fe29d6dec874/joph2021-4694577.001.jpg

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