[大剂量和小剂量维生素E对蛙肌细胞兴奋性的影响]
[Effects of large and small doses of vitamin E on the excitability of frog myocytes].
作者信息
Satybaldina N K, Frolov V A
出版信息
Biull Eksp Biol Med. 1989 Oct;108(10):398-9.
PMID:2597748
Abstract
The effect of the fat-soluble vitamin E on electrophysiological characteristics was investigated on frog cardiomyocytes. Large and small doses of vitamin E produced qualitatively identical effects: shortening of the plateau and decrease of the AP--duration. We assume that large doses of vitamin E can affect the cardiomyocytes membrane transport function, mainly due to the activation of slow membrane channels.
摘要
研究了脂溶性维生素E对青蛙心肌细胞电生理特性的影响。大剂量和小剂量的维生素E产生了定性相同的效果：平台期缩短和动作电位（AP）时程缩短。我们认为大剂量的维生素E可影响心肌细胞膜转运功能，主要是由于慢膜通道的激活。
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