L'Esperance F A, Taylor D M, Warner J W
Bull N Y Acad Med. 1989 Jun;65(5):557-73.
The first human trial utilizing the argon fluoride excimer laser at 193 nm to produce a superficial keratectomy in the initial three of 10 human eyes has been described with the clinical appearance and short-term (less than 14 days) histopathologic evaluation of these three eyes. The process of laser superficial keratectomy has proved one of the promising areas of surgical intervention for reconstructive or refractive keratoplasty in the future. Intensive investigations of corneal wound healing following laser ablation as well as the nature and long-term stability of the corneal excisions or induced refractive corrections are needed. It is essential that the optimal laser parameters be established for the various refractive corrections and other corneal surgical techniques and that pathophysiologic and histopathologic changes that have been induced by the excimer laser-corneal tissue interaction in animals and humans be critically and extensively analysed.
首次在10只人眼中的前3只眼睛上利用193纳米的氟化氩准分子激光进行表面角膜切除术的人体试验，已对这3只眼睛的临床表现和短期（少于14天）组织病理学评估进行了描述。激光表面角膜切除术已被证明是未来用于重建性或屈光性角膜移植手术干预的有前景的领域之一。需要对激光消融后的角膜伤口愈合以及角膜切除或诱导的屈光矫正的性质和长期稳定性进行深入研究。至关重要的是，要为各种屈光矫正和其他角膜手术技术确定最佳激光参数，并对动物和人类中准分子激光与角膜组织相互作用所引起的病理生理和组织病理学变化进行严格而广泛的分析。
