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汉族人群低盐干预的动态血压和血压负荷反应。

Ambulatory blood pressure and blood pressure load responses to low sodium intervention in Han Chinese population.

机构信息

a Department of Epidemiology, State Key Laboratory of Cardiovascular Disease , Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , P.R. China.

出版信息

Clin Exp Hypertens. 2015;37(7):551-6. doi: 10.3109/10641963.2015.1026038. Epub 2015 May 15.

DOI:10.3109/10641963.2015.1026038
PMID:25978271
Abstract

We aimed to illustrate ambulatory blood pressure monitoring parameters responses to low sodium intake and their differences between salt-sensitive and non-salt-sensitive individuals. A total of 186 participants were included in this analysis. Twenty-four hour, day-time and night-time blood pressure (BP) and BP load decreased during low sodium intervention, especially in salt-sensitive (SS) group. After multivariable adjustment, 24-h systolic BP, diastolic BP, mean arterial pressure and BP load responses to low sodium intervention of SS individuals were more pronounced than those of non-salt-sensitive individuals. Thus, reducing salt intake is potentially needed for the prevention of hypertension, especially in SS individuals.

摘要

我们旨在说明低钠摄入对动态血压监测参数的影响及其在盐敏感和非盐敏感个体之间的差异。本分析共纳入 186 名参与者。低钠干预期间,24 小时、白天和夜间血压(BP)和 BP 负荷降低,尤其是在盐敏感(SS)组。多变量调整后,SS 个体对低钠干预的 24 小时收缩压、舒张压、平均动脉压和 BP 负荷反应比非盐敏感个体更明显。因此,减少盐的摄入可能有助于预防高血压,尤其是在 SS 个体中。

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