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美国性传播感染中的种族差异:同时性行为、性传播感染患病率及性伴侣选择的异质性。

The racial disparities in STI in the U.S.: Concurrency, STI prevalence, and heterogeneity in partner selection.

作者信息

Hamilton Deven T, Morris Martina

机构信息

Center for Studies in Demography and Ecology, University of Washington, United States.

Department of Statistics, University of Washington, United States; Department of Sociology, University of Washington, United States.

出版信息

Epidemics. 2015 Jun;11:56-61. doi: 10.1016/j.epidem.2015.02.003. Epub 2015 Feb 19.

Abstract

BACKGROUND

There is a large and persistent racial disparity in STI in the U.S. which has placed non-Hispanic-Blacks at disproportionately high risk. We tested a hypothesis that both individual-level risk factors (partner number, anal sex, condom use) and local-network features (concurrency and assortative mixing by race) combine to account for the association between race and chlamydia status.

METHODS

Data from the Longitudinal Survey of Adolescent Health Wave III were used. Chlamydia status was determined using biomarkers. Individual-level risk behaviors were self-reported. Network location variables for concurrency and assortative mixing were imputed using egocentrically sample data on sexual partnerships.

RESULTS

After controlling for demographic attributes including age, sex, marital status, education and health care access there remained a strong association between race and chlamydia status (OR = 5.23, 95% CI [3.83-7.15], p < .001 for Non-Hispanic Blacks with Non-Hispanic Whites as the reference category). The inclusion of individual-level risk factors did not alter the association between race and chlamydia (OR = 5.23 for Non-Hispanic Blacks). The inclusion of concurrency and assortative mixing by race substantially reduced the association between race and chlamydia status (OR = 1.87, 95% CI [0.89-3.91] p > .05 for Non-Hispanic Blacks).

摘要

背景

在美国,性传播感染(STI)方面存在巨大且持续的种族差异,这使得非西班牙裔黑人面临的风险极高。我们检验了一个假设,即个体层面的风险因素(性伴侣数量、肛交、使用避孕套)和本地网络特征(性伴侣更替频率以及按种族的选择性混合)共同导致了种族与衣原体感染状况之间的关联。

方法

使用了青少年健康纵向调查第三波的数据。衣原体感染状况通过生物标志物确定。个体层面的风险行为通过自我报告获取。性伴侣更替频率和选择性混合的网络位置变量使用以自我为中心的性伴侣样本数据进行估算。

结果

在控制了包括年龄、性别、婚姻状况、教育程度和医疗保健可及性等人口统计学属性后,种族与衣原体感染状况之间仍存在强烈关联(以非西班牙裔白人为参照类别,非西班牙裔黑人的比值比[OR]=5.23,95%置信区间[CI][3.83 - 7.15],p<.001)。纳入个体层面的风险因素并未改变种族与衣原体感染之间的关联(非西班牙裔黑人的OR = 5.23)。纳入性伴侣更替频率和按种族的选择性混合后,种族与衣原体感染状况之间的关联大幅降低(非西班牙裔黑人的OR = 1.87,95% CI[0.89 - 3.91],p>.05)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d565/4435828/59ef938bf234/nihms672094f1.jpg

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