Lucchetti Maria Claudia, Fratto Giovanni, Valeriani Federica, De Vittori Elisabetta, Giampaoli Saverio, Papetti Patrizia, Romano Spica Vincenzo, Manzon Licia
Professor, Department of Business Studies, University RomaTRE, Rome, Italy.
Professor, Department of Dental Material, University of Rome "La Sapienza," Rome, Italy.
J Prosthet Dent. 2015 Oct;114(4):602-8. doi: 10.1016/j.prosdent.2015.03.002. Epub 2015 Jun 5.
Metal ions released into the oral cavity from dental prosthesis alloys may damage the cellular metabolism or proliferation and cause hypersensitivity or allergies. The oral cavity environment is particularly prone to corrosion due to saliva, microorganisms, and pH variations.
The purpose of this in vitro study was to evaluate the ion release of chromium, cobalt, and iron from the Co-Cr alloys used for traditionally cast and computer-aided design/computer-aided manufacturing dental devices after interaction with oral bacteria and different pH conditions.
All specimens were prepared from currently available alloys, polished, and immersed in 3 different pH media (artificial saliva [pH 2.3] and 6.5% and 0.9% saline solution [pH 7.1]). Specimens were also incubated in the presence of the bacterium Eikenella corrodens. Solutions were analyzed with an atomic absorption spectrometer after 15 and 30 days in the chemical corrosion test and 30 days in the biocorrosion test to detect ions released in different solutions. An ANOVA test was used to evaluate statistically significant differences among the percentages of metal corrosion ion release values.
The greatest amount of element release was seen after 30 days: 4.964 ppm of casting alloy, 2.642 ppm of milling alloy, and 2.351 ppm of laser metal sintering.
With the exception of casting alloy under acidic conditions, no significant differences were found, even after exposure to bacteria.
从牙科修复合金释放到口腔中的金属离子可能会损害细胞代谢或增殖，并导致超敏反应或过敏。由于唾液、微生物和pH值变化，口腔环境特别容易发生腐蚀。
本体外研究的目的是评估在与口腔细菌相互作用以及不同pH条件下，用于传统铸造和计算机辅助设计/计算机辅助制造牙科器械的钴铬合金中铬、钴和铁的离子释放情况。
所有标本均由市售合金制备，抛光后浸入3种不同pH值的介质中（人工唾液[pH 2.3]以及6.5%和0.9%的盐溶液[pH 7.1]）。标本还在腐蚀艾肯菌存在的情况下进行孵育。在化学腐蚀试验的15天和30天后以及生物腐蚀试验的30天后，用原子吸收光谱仪分析溶液，以检测不同溶液中释放的离子。采用方差分析来评估金属腐蚀离子释放值百分比之间的统计学显著差异。
30天后元素释放量最大：铸造合金为4.964 ppm，铣削合金为2.642 ppm，激光金属烧结合金为2.351 ppm。
除酸性条件下的铸造合金外，即使在接触细菌后也未发现显著差异。
