嘌呤能信号在肌肉骨骼系统中的作用。
The role of purinergic signalling in the musculoskeletal system.
作者信息
Orriss Isabel R
机构信息
Department of Comparative Biomedical Sciences, Royal Veterinary College, Royal College Street, London NW1 0TU, United Kingdom.
出版信息
Auton Neurosci. 2015 Sep;191:124-34. doi: 10.1016/j.autneu.2015.04.013. Epub 2015 May 7.
PMID:25979767
Abstract
Accumulating evidence now suggests that purinergic signalling exerts significant regulatory effects in the musculoskeletal system. In particular, it has emerged that extracellular nucleotides are key regulators of bone cell differentiation, survival and function. This review discusses our current understanding of the direct effects of purinergic signalling in bone, cartilage and muscle.
摘要
越来越多的证据表明，嘌呤能信号在肌肉骨骼系统中发挥着重要的调节作用。特别是，细胞外核苷酸已成为骨细胞分化、存活和功能的关键调节因子。本文综述了我们目前对嘌呤能信号在骨骼、软骨和肌肉中直接作用的理解。
Zotero 插件