Seckin Mustafa, Mesulam M-Marsel, Rademaker Alfred W, Voss Joel L, Weintraub Sandra, Rogalski Emily J, Hurley Robert S
a Cognitive Neurology and Alzheimer's Disease Center , Northwestern University , Chicago , IL , USA.
b Department of Preventive Medicine , Northwestern University , Chicago , IL , USA.
Neurocase. 2016;22(1):65-75. doi: 10.1080/13554794.2015.1045523. Epub 2015 May 18.
Eye movement trajectories during a verbally cued object search task were used as probes of lexico-semantic associations in an anomic patient with primary progressive aphasia. Visual search was normal on trials where the target object could be named but became lengthy and inefficient on trials where the object failed to be named. The abnormality was most profound if the noun denoting the object could not be recognized. Even trials where the name of the target object was recognized but not retrieved triggered abnormal eye movements, demonstrating that retrieval failures can have underlying associative components despite intact comprehension of the corresponding noun.
在一项言语提示的物体搜索任务中，眼球运动轨迹被用作一名原发性进行性失语失命名患者词汇语义联想的探测指标。在目标物体能够被命名的试验中，视觉搜索正常，但在物体无法被命名的试验中，搜索变得冗长且低效。如果表示物体的名词无法被识别，这种异常最为明显。即使在目标物体的名称被识别但未被提取的试验中，也会引发异常的眼球运动，这表明尽管对相应名词的理解完整，但提取失败可能具有潜在的联想成分。
