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德国糖尿病患者群体中肾病的患病率——如今早期转诊至肾病专科护理是否是一项现实的要求?

Prevalence of nephropathy in the German diabetes population-Is early referral to nephrological care a realistic demand today?

作者信息

Pommer Wolfgang

机构信息

Department of Internal Medicine-Nephrology , Vivantes Humboldt Hospital , Berlin , Germany.

出版信息

NDT Plus. 2008 Oct;1(Suppl 4):iv2-iv5. doi: 10.1093/ndtplus/sfn115.

Abstract

In Germany, diabetes mellitus in the general population has increased to ∼8 million people. The implication of this trend for future nephrological care is not well known, as data on this issue are rather limited. Results from different population-based studies suggest that microalbuminuria in diabetic patients is present in 20-30% of the cases. Findings from the diabetes disease management programme in the North-Rhine area revealed the prevalence of chronic kidney disease (CKD) stage II in half of the participants (CKD stage III was present in ∼20%). Only a small proportion of this cohort (∼1-2%) will reach end-stage renal failure, probably due to the excess mortality risks attributed to advanced kidney disease. Results from the QUASI-Niere registry, which reports on renal replacement therapy in Germany, indicate almost constant incidence and prevalence rates of diabetes in the last 5 years (30.6-34.2% and 23.6-27.1%, respectively). The high percentages of early stages of CKD in the diabetes population indicate a potentially high burden of future nephrological care, especially if patients are referred to nephrologists at an early stage. In reality, in nephrological care, bearing this burden is impossible without expanding the resources for this patient group.

摘要

在德国,普通人群中的糖尿病患者已增至约800万人。由于关于这一问题的数据相当有限,这一趋势对未来肾脏疾病护理的影响尚不清楚。不同人群研究的结果表明,20%-30%的糖尿病患者存在微量白蛋白尿。北莱茵地区糖尿病疾病管理项目的研究结果显示,一半参与者患有慢性肾脏病(CKD)II期(约20%患有CKD III期)。该队列中只有一小部分人(约1%-2%)会发展到终末期肾衰竭,这可能是由于晚期肾病带来的额外死亡风险。德国肾脏替代治疗报告QUASI-Niere登记处的结果表明,过去5年糖尿病的发病率和患病率几乎保持不变(分别为30.6%-34.2%和23.6%-27.1%)。糖尿病患者中CKD早期的高比例表明未来肾脏疾病护理可能负担沉重,尤其是如果患者在早期就转诊至肾脏科医生处。实际上,在肾脏疾病护理中,如果不为这一患者群体增加资源,就不可能承担这一负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc01/4421149/ed62a4aac163/sfn115fig1.jpg

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