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使用大五人格问卷对边缘型人格障碍进行基于特质的评估:表型和遗传支持。

Trait-based assessment of borderline personality disorder using the NEO Five-Factor Inventory: Phenotypic and genetic support.

作者信息

Few Lauren R, Miller Joshua D, Grant Julia D, Maples Jessica, Trull Timothy J, Nelson Elliot C, Oltmanns Thomas F, Martin Nicholas G, Lynskey Michael T, Agrawal Arpana

机构信息

Department of Psychiatry, Washington University School of Medicine.

Department of Psychology, University of Georgia.

出版信息

Psychol Assess. 2016 Jan;28(1):39-50. doi: 10.1037/pas0000142. Epub 2015 May 18.

Abstract

[Correction Notice: An Erratum for this article was reported in Vol 28(1) of Psychological Assessment (see record 2015-54029-001). The FFI-BPD values for Sample 3 in Table 2 should read 1.42 (0.44), 0.83.] The aim of the current study was to examine the reliability and validity of a trait-based assessment of borderline personality disorder (BPD) using the NEO Five-Factor Inventory. Correlations between the Five-Factor Inventory-BPD composite (FFI-BPD) and explicit measures of BPD were examined across 6 samples, including undergraduate, community, and clinical samples. The median correlation was .60, which was nearly identical to the correlation between measures of BPD and a BPD composite generated from the full Revised NEO Personality Inventory (i.e., NEO-BPD; r = .61). Correlations between FFI-BPD and relevant measures of psychiatric symptomatology and etiology (e.g., childhood abuse, drug use, depression, and personality disorders) were also examined and compared to those generated using explicit measures of BPD and NEO-BPD. As expected, the FFI-BPD composite correlated most strongly with measures associated with high levels of Neuroticism, such as depression, anxiety, and emotion dysregulation, and the pattern of correlations generated using the FFI-BPD was highly similar to those generated using explicit measures of BPD and NEO-BPD. Finally, genetic analyses estimated that FFI-BPD is 44% heritable, which is comparable to meta-analytic research examining genetics associated with BPD, and revealed that 71% of the genetic influences are shared between FFI-BPD and a self-report measure assessing BPD (Personality Assessment Inventory-Borderline subscale; Morey, 1991). Generally, these results support the use of FFI-BPD as a reasonable proxy for BPD, which has considerable implications, particularly for potential gene-finding efforts in large, epidemiological datasets that include the NEO FFI.

摘要

[更正通知:本文的一份勘误报告发表在《心理评估》第28卷第1期(见记录2015-54029-001)。表2中样本3的FFI-BPD值应为1.42(0.44),0.83。]本研究旨在使用大五人格问卷(NEO)检验基于特质的边缘型人格障碍(BPD)评估的信效度。在包括本科生、社区样本和临床样本在内的6个样本中,检验了五因素问卷-BPD综合量表(FFI-BPD)与BPD显性测量指标之间的相关性。中位数相关性为0.60,这与BPD测量指标与由完整修订版大五人格问卷生成的BPD综合量表(即NEO-BPD;r = 0.61)之间的相关性几乎相同。还检验了FFI-BPD与精神症状学和病因学相关测量指标(如童年期虐待、药物使用、抑郁和人格障碍)之间的相关性,并与使用BPD显性测量指标和NEO-BPD生成的相关性进行了比较。正如预期的那样,FFI-BPD综合量表与与高神经质水平相关的测量指标相关性最强,如抑郁、焦虑和情绪失调,并且使用FFI-BPD生成的相关模式与使用BPD和NEO-BPD显性测量指标生成的模式高度相似。最后,基因分析估计FFI-BPD的遗传度为44%,这与研究BPD相关遗传学的元分析研究结果相当,并且表明71%的遗传影响在FFI-BPD和一项评估BPD的自我报告测量指标(人格评估问卷-边缘型分量表;莫雷,1991)之间是共享的。总体而言,这些结果支持将FFI-BPD用作BPD的合理替代指标,这具有相当大的意义,特别是对于包含NEO FFI的大型流行病学数据集中潜在的基因发现工作而言。

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