Gangat M Azhar, Hsu Jennifer L
S D Med. 2015;Spec No:44-8.
Antibiotic resistance is one of the major health threats facing modern medicine. While there are many tactics to address this issue, antibiotic stewardship has been shown effective in reducing antimicrobial resistance, adverse drug effects, mortality and health care cost. Most antibiotic stewardship programs have evolved within acute care settings where the bulk of resistant infections are identified. Unfortunately, hospitals are just the tip of the iceberg in terms of overall antibiotic use. The vast majority of the antibiotic prescriptions are dispensed in ambulatory care settings, making this a critical target for stewardship programs. This article discusses the global need for antibiotic stewardship, highlights the importance of outpatient stewardship, and discusses strategies and challenges for implementation of stewardship in community settings.
抗生素耐药性是现代医学面临的主要健康威胁之一。虽然有许多应对这一问题的策略，但抗生素管理已被证明在降低抗菌药物耐药性、药物不良反应、死亡率和医疗保健成本方面是有效的。大多数抗生素管理计划是在急性护理环境中发展起来的，在这些环境中发现了大部分耐药感染。不幸的是，就抗生素的总体使用而言，医院只是冰山一角。绝大多数抗生素处方是在门诊护理环境中开具的，这使其成为管理计划的关键目标。本文讨论了全球对抗生素管理的需求，强调了门诊管理的重要性，并讨论了在社区环境中实施管理的策略和挑战。
