Ge Z M, Zhang Y, Gao D C
Zhonghua Nei Ke Za Zhi. 1989 Aug;28(8):460-2, 508.
31 patients undergoing diagnostic cardiac catheterization for suspected congenital heart disease and 30 normal subjects were examined by pulsed Doppler echocardiography. Spectrum analysis of the shape of flow velocity curve and instantaneous flow velocities of the pulmonary artery during systolic period was made and their ratio calculated. The results showed that there was a remarkable difference between the flow velocity curve of pulmonary hypertension (PH) and that of normal pulmonary pressure. Combining with the characteristics of pulmonary arterial hemodynamics, a preliminary exploration was made on the mechanism of flow velocity curve changes. A ratio of flow velocities--PV% was proposed. The sensitivity and specificity for diagnosing PH with PV% were 94% and 100% respectively. There was a high correlation between PV% and pulmonary artery systolic pressure (r = -0.84) or pulmonary artery mean pressure (r = -0.82). It is concluded that PV% may eliminate many factors that influence the pulmonary artery hemodynamics and is a reliable, practical qualitative and quantitative index for diagnosing PH noninvasively.
对31例疑似先天性心脏病而接受诊断性心导管检查的患者及30名正常受试者进行了脉冲多普勒超声心动图检查。对收缩期肺动脉血流速度曲线的形状及瞬时血流速度进行频谱分析，并计算其比值。结果显示，肺动脉高压（PH）的血流速度曲线与正常肺动脉压力者的血流速度曲线存在显著差异。结合肺动脉血流动力学特点，对血流速度曲线变化机制进行了初步探讨。提出了一个血流速度比值——PV%。用PV%诊断PH的敏感性和特异性分别为94%和100%。PV%与肺动脉收缩压（r = -0.84）或肺动脉平均压（r = -0.82）之间存在高度相关性。结论是，PV%可消除许多影响肺动脉血流动力学的因素，是一种可靠、实用的无创诊断PH的定性和定量指标。
