Godoy Maria Dantas Costa Lima, Voegels Richard Louis, Pinna Fábio de Rezende, Imamura Rui, Farfel José Marcelo
Department of Otorhinolaryngology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Department of Geriatrics, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Int Arch Otorhinolaryngol. 2015 Apr;19(2):176-9. doi: 10.1055/s-0034-1390136. Epub 2014 Nov 14.
Introduction Loss of smell is involved in various neurologic and neurodegenerative diseases, such as Parkinson disease and Alzheimer disease. However, the olfactory test is usually neglected by physicians at large. Objective The aim of this study was to review the current literature about the relationship between olfactory dysfunction and neurologic and neurodegenerative diseases. Data Synthesis Twenty-seven studies were selected for analysis, and the olfactory system, olfaction, and the association between the olfactory dysfunction and dementias were reviewed. Furthermore, is described an up to date in olfaction. Conclusion Otolaryngologist should remember the importance of olfaction evaluation in daily practice. Furthermore, neurologists and physicians in general should include olfactory tests in the screening of those at higher risk of dementia.
引言 嗅觉丧失与多种神经和神经退行性疾病有关，如帕金森病和阿尔茨海默病。然而，嗅觉测试通常被广大医生所忽视。目的 本研究的目的是回顾当前关于嗅觉功能障碍与神经和神经退行性疾病之间关系的文献。资料综合 选取27项研究进行分析，对嗅觉系统、嗅觉以及嗅觉功能障碍与痴呆之间的关联进行了综述。此外，还介绍了嗅觉方面的最新情况。结论 耳鼻喉科医生在日常实践中应牢记嗅觉评估的重要性。此外，神经科医生和普通医生在对痴呆高危人群进行筛查时应纳入嗅觉测试。
