Grytdal Scott P, Rimland David, Shirley S Hannah, Rodriguez-Barradas Maria C, Goetz Matthew Bidwell, Brown Sheldon T, Lucero-Obusan Cynthia, Holodniy Mark, Graber Christopher, Parashar Umesh, Vinjé Jan, Lopman Ben
Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Atlanta VA Medical Center and Emory University School of Medicine, Atlanta, Georgia, United States of America.
PLoS One. 2015 May 21;10(5):e0126733. doi: 10.1371/journal.pone.0126733. eCollection 2015.
An estimated 179 million acute gastroenteritis (AGE) illnesses occur annually in the United States. The role of noroviruses in hospital-related AGE has not been well-documented in the U. S. We estimated the population incidence of community- acquired outpatient and inpatient norovirus AGE encounters, as well as hospital-acquired inpatient norovirus AGE among inpatients at four Veterans Affairs (VA) Medical Centers (VAMCs). Fifty (4%) of 1,160 stool specimens collected ≤7 days from symptom onset tested positive for norovirus. During a one year period, the estimated incidence of outpatient, community- and hospital-acquired inpatient norovirus AGE was 188 cases, 11 cases, and 54 cases/ 100,000 patients, respectively. This study demonstrates the incidence of outpatient and community- and hospital-acquired inpatient norovirus AGE among the VA population seeking care at these four VAMCs.
据估计,美国每年发生约1.79亿例急性肠胃炎(AGE)疾病。在美国,诺如病毒在医院相关急性肠胃炎中的作用尚未得到充分记录。我们估算了四家退伍军人事务(VA)医疗中心(VAMC)中社区获得性门诊和住院诺如病毒急性肠胃炎病例的人群发病率,以及住院患者中医院获得性住院诺如病毒急性肠胃炎的发病率。从症状出现起7天内采集的1160份粪便样本中,有50份(4%)诺如病毒检测呈阳性。在一年期间,门诊、社区获得性和医院获得性住院诺如病毒急性肠胃炎的估计发病率分别为每10万名患者188例、11例和54例。这项研究表明了在这四家VAMC寻求治疗的VA人群中门诊、社区获得性和医院获得性住院诺如病毒急性肠胃炎的发病率。