Fartasch Manigé, Diepgen Thomas L, Drexler Hans, Elsner Peter, John Swen Malte, Schliemann Sibylle
Department of Clinical and Experimental Occupational Dermatology, Institute for Prevention and Occupational Medicine of the German Occupational Accident Insurance, Institute of the Ruhr University Bochum (IPA), Germany.
Department of Clinical Social Medicine, Occupational and Environmental Dermatology, Ruprecht Karls University Heidelberg, Germany.
J Dtsch Dermatol Ges. 2015 Jun;13(6):594-606. doi: 10.1111/ddg.12617. Epub 2015 May 22.
Job-related hand dermatitis heads up the list of reported occupational diseases. So-called skin products - understood to mean protective creams, skin cleansers and skin care products - are used for the primary and secondary prevention of job- related hand dermatitis. In the interests of evidence-based medicine, the only preventive measures and/or occupational skin products that should be used are those whose potential uses and efficacy are underpinned by scientific research. To this end, the Arbeitsgemeinschaft für Berufs- und Umweltdermatologie e.V. (Working Group for Occupational and Environmental Dermatology, ABD) of the DDG (German Dermatological Society) and the Deutsche Gesellschaft für Arbeits- und Umweltmedizin (German Society for Occupational and Environmental Medicine, DGAUM) have summed up the latest scientific findings and recommendations in the updated guideline. The benefit of the combined application of protective creams and skin care products in the primary and secondary prevention of work-related contact dermatitis has been widely confirmed by recent clinical-epidemiological studies. The guideline clearly explains the necessity of demonstrating the efficacy of protective creams and cleansing products by means of in vivo methods in the sense of repetitive applications. Transferable standardised testing systems designed to examine the irritation potential and thus the compatibility of occupational skin cleansers and the reduction of irritation by protective skin creams have now been developed and validated by multicentre studies for skin protection creams and cleansers. The status of the current assessment of the safety of occupational skin products is also summarised.
职业性手部皮炎在报告的职业病列表中位居首位。所谓的皮肤产品——被理解为防护霜、皮肤清洁剂和护肤品——用于职业性手部皮炎的一级和二级预防。为了循证医学的利益,应使用的唯一预防措施和/或职业性皮肤产品是那些其潜在用途和功效有科学研究支持的产品。为此,德国皮肤病学会(DDG)的职业与环境皮肤病学工作小组(Arbeitsgemeinschaft für Berufs- und Umweltdermatologie e.V.,ABD)和德国职业与环境医学学会(Deutsche Gesellschaft für Arbeits- und Umweltmedizin,DGAUM)在更新的指南中总结了最新的科学发现和建议。近期临床流行病学研究广泛证实了防护霜和护肤品联合应用在一级和二级预防工作相关接触性皮炎中的益处。该指南明确解释了通过重复应用的体内方法证明防护霜和清洁产品功效的必要性。现已开发出可转移的标准化测试系统,用于检测职业性皮肤清洁剂的刺激潜力以及与防护性护肤霜的兼容性,并通过多中心研究对护肤霜和清洁剂进行了验证。文中还总结了职业性皮肤产品当前安全性评估的状况。