Vellone Valerio Gaetano, Calamaro Paola, Vignale Cristina, Novaro Gianni, Penna Lucia, Fulcheri Ezio
University of Genoa, Genoa, Italy
University of Genoa, Genoa, Italy.
Int J Surg Pathol. 2015 Aug;23(5):364-8. doi: 10.1177/1066896915585347. Epub 2015 May 20.
Chorangiomas are rather frequent neoplasms encountered on placental examination but in rare cases they present some worrisome histological features that could alarm the pathologist and be misinterpreted as a malignant neoplasm, even if their biological behavior is favorable. We describe an unusual chorangioma with high cellularity and abundant mitosis that, after careful examination and postpartum follow-up, showed benign clinical course for mother and child confirming previous reported cases. This type of tumor is known in the literature as atypical cellular chorangioma and its identification is important in order to exclude potentially dangerous overtreatment.
绒毛膜血管瘤是胎盘检查中较为常见的肿瘤，但在极少数情况下，它们会呈现出一些令人担忧的组织学特征，这可能会让病理学家感到警觉，并被误诊为恶性肿瘤，尽管其生物学行为是良性的。我们描述了一例具有高细胞密度和丰富有丝分裂的罕见绒毛膜血管瘤，经过仔细检查和产后随访，显示母婴临床过程良好，这证实了之前报道的病例。这种类型的肿瘤在文献中被称为非典型细胞性绒毛膜血管瘤，其识别对于排除潜在危险的过度治疗很重要。
