Rühli Frank J
Swiss Mummy Project, Centre for Evolutionary Medicine, Institute of Anatomy, University of Zurich, Winterthurerstr. 190, Zürich, 8057, Switzerland.
Anat Rec (Hoboken). 2015 Jun;298(6):1111-5. doi: 10.1002/ar.23150.
Noninvasive imaging of ancient tissues is of increasing interest in palaeopathological studies, with conventional X-ray and computed tomography currently considered the diagnostic gold standard. Convenitional X-ray has a long tradition, yet imaging of ancient mummies using conventional X-ray technique has its drawbacks too. Until recently, magnetic resonance imaging (MRI) of soft tissues was successful with ancient dry tissues only after morphology-altering rehydration. This process was deemed necessary due to the previous reported lack of unbound protons. Hitherto, any approach without rehydration of the historic samples failed. Yet, the successful application of novel MRI techniques allows broadening of the methodological spectrum of methods for noninvasive studies on ancient corpses, whether they have wet or dry soft tissue, or bone. Spatial discrimination of chemical elements can now be carried out with high sensitivity in any historic specimen, leading to an increased level of diagnostic evidence.
在古病理学研究中,对古代组织的无创成像越来越受到关注,传统的X射线和计算机断层扫描目前被视为诊断金标准。传统X射线有着悠久的历史,但使用传统X射线技术对古代木乃伊进行成像也有其缺点。直到最近,软组织的磁共振成像(MRI)仅在对古代干组织进行形态改变的复水后才取得成功。由于先前报道的缺乏游离质子,这一过程被认为是必要的。迄今为止,任何不对历史样本进行复水的方法都失败了。然而,新型MRI技术的成功应用拓宽了对古代尸体进行无创研究的方法学范围,无论这些尸体的软组织是湿的还是干的,或者是骨骼。现在可以在任何历史标本中高灵敏度地进行化学元素的空间辨别,从而提高诊断证据的水平。