银屑病与代谢综合征。
Psoriasis and metabolic syndrome.
作者信息
Malkic Salihbegovic Eldina, Hadzigrahic Nermina, Cickusic Amra Jakubovic
机构信息
Health Center Zivinice, Zivinice, Bosnia and Herzegovina.
University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.
出版信息
Med Arch. 2015 Apr;69(2):85-7. doi: 10.5455/medarh.2015.69.85-87. Epub 2015 Apr 6.
INTRODUCTION
Psoriasis is a chronic skin ailment which can be connected with an increased occurrence of other illnesses, including the metabolic syndrome.
EXAMINEES AND METHODS
A prospective study has been conducted which included 70 patients affected by psoriasis, both genders, older than 18 years. Average age being 47,14 (SD=±15,41) years, from that there were 36 men or 51,43 and 34 women or 48,57%. The average duration of psoriasis was 15,52 (SD= ±12,54) years. For purposes of diagnosing the metabolic syndrome, the criteria of National Cholesterol Education Program Adult Treatment Panel III, (NCEP ATP III) were used. For purposes of detecting the severity and spread of psoriasis, Psoriasis Area and Severity Index (PASI) was used.
RESULTS
The incidence of metabolic syndrome in patients with psoriasis was 38,57%. Average values of PASI score were 16,65. The increase in values of PASI score and metabolic syndrome were statistically highly connected. (r=0,3, p=0,0001).
CONCLUSION
Psoriasis is connected with metabolic syndrome, there is a positive correlation between the severity of psoriasis and frequency of metabolic syndrome.
引言
银屑病是一种慢性皮肤病，可能与包括代谢综合征在内的其他疾病的发病率增加有关。
受试者与方法
进行了一项前瞻性研究，纳入了70例年龄超过18岁的银屑病患者，男女不限。平均年龄为47.14（标准差=±15.41）岁，其中男性36例，占51.43%，女性34例，占48.57%。银屑病的平均病程为15.52（标准差=±12.54）年。为诊断代谢综合征，采用了美国国家胆固醇教育计划成人治疗小组第三次报告（NCEP ATP III）的标准。为检测银屑病的严重程度和范围，使用了银屑病面积和严重程度指数（PASI）。
结果
银屑病患者中代谢综合征的发病率为38.57%。PASI评分的平均值为16.65。PASI评分值的增加与代谢综合征在统计学上高度相关（r=0.3，p=0.0001）。
结论
银屑病与代谢综合征有关，银屑病的严重程度与代谢综合征的发生率之间存在正相关。
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