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基层医疗中未做调查的消化不良管理新方法。

A new approach to the management of uninvestigated dyspepsia in primary care.

作者信息

Salihefendic Nizama, Zildzic Muharem, Cabric Emir

机构信息

Department of Emergency Medicine, Faculty of medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina ; Medicus A Gracanica, Gracanica, Bosnia and Herzegovina.

Medicus A Gracanica, Gracanica, Bosnia and Herzegovina.

出版信息

Med Arch. 2015 Apr;69(2):133-4. doi: 10.5455/medarh.2015.69.133-134. Epub 2015 Apr 6.

Abstract

INTRODUCTION

The prevalence of dyspepsia in the general population worldwide is very high (20-40%). Upper abdominal complaints are one of the most common cause of patients' visits to primary care settings. Making an accurate etiological diagnosis of dyspepsia is difficult, but is an important challenge and goal for every doctor in primary care practice. Clinical guidelines have standards for gastroesophageal reflux disease, management of Helicobacter infection and indications for the use of endoscopy (empiric treatment, prompt endoscopy, "test and treat"). In spite of the application of those standards, many patients experience no improvement in their symptoms or often the recurrence of disease.

AIM

This study presents a new approach to the diagnostic and therapeutic management of uninvestigated dyspepsia in primary care settings to provide long-term effective control of symptoms for family doctors.

MATERIAL AND METHODS

3000 unselected consecutive dyspeptic patients underwent abdominal ultrasound, and 1000 dyspeptic patients from the same group upper endoscopy.. In this approach diagnostic evaluation of dyspepsia includes: abdominal ultrasonography as a first line obligatory routine method and the exact estimation of nutritional condition.

RESULTS

Abdominal ultrasound, physical examination and BMI control have significant value in the diagnostic evaluation of dyspepsia. The therapeutic approach includes, besides general standards (acid suppressive drugs, eradication of H. pylori, prokinetic and antidepressant agents), life style modification and nutritional interventions as first-line treatments. In this approach the use of new drugs such as ursodeoxycholic acid (UDCA), pre and probiotics, and digestive enzymes supplements is recommended.

CONCLUSION

Throug the combination of different diagnostic procedures as first line methods, including abdominal ultrasound and nutritional condition (BMI), a family doctor can manage successfully uninvestigated dyspepsia at the primary care level.

摘要

引言

全球普通人群中消化不良的患病率非常高(20%-40%)。上腹部不适是患者前往基层医疗机构就诊的最常见原因之一。准确做出消化不良的病因诊断很困难,但这是基层医疗实践中每位医生面临的重要挑战和目标。临床指南对胃食管反流病、幽门螺杆菌感染的管理以及内镜检查的指征(经验性治疗、及时内镜检查、“检测和治疗”)都有标准。尽管应用了这些标准,许多患者的症状并未改善,或者疾病常常复发。

目的

本研究提出一种针对基层医疗中未经检查的消化不良的诊断和治疗管理的新方法,为家庭医生提供对症状的长期有效控制。

材料与方法

3000例未经挑选的连续消化不良患者接受了腹部超声检查,同一组中的1000例消化不良患者接受了上消化道内镜检查。在这种方法中,消化不良的诊断评估包括:腹部超声作为一线必做的常规方法以及对营养状况的准确评估。

结果

腹部超声、体格检查和体重指数控制在消化不良的诊断评估中具有重要价值。治疗方法除了一般标准(抑酸药物、根除幽门螺杆菌、促动力剂和抗抑郁药)外,还包括生活方式改变和营养干预作为一线治疗。在这种方法中,推荐使用熊去氧胆酸(UDCA)、益生元和益生菌以及消化酶补充剂等新药。

结论

通过将不同的诊断程序(包括腹部超声和营养状况(体重指数))作为一线方法相结合,家庭医生可以在基层医疗层面成功管理未经检查的消化不良。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c1/4430015/480a4ca43e46/MA-69-133-g004.jpg

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