Bhargava Rahul, Kumar Prachi, Phogat Hemant, Chaudhary Kulbhushan Prakash
Department of Ophthalmology, Laser Eye Clinic, Noida, Uttar Pradesh, India.
Department of Pathology, Santosh Medical College and Hospital, Ghaziabad, India.
J Ophthalmic Vis Res. 2015 Jan-Mar;10(1):37-42. doi: 10.4103/2008-322X.156101.
To study factors affecting laser energy levels required for neodymium: yttrium aluminium garnet (Nd: YAG) laser capsulotomy and to evaluate whether any correlation exists between applied laser energy levels and complications.
The present study examined 474 consecutive patients for a number of factors including age, type of posterior capsule opacification (PCO), material and fixation of intraocular lens (IOL) and complication rates, versus energy levels used for Nd: YAG laser capsulotomy.
Mean patient age was 55.6 ± 8.7 years and mean follow up period was 22.9 ± 4.5 months. IOL biomaterial (KW ANOVA; P = 0.173) and patient's age (P = 0.246) did not significantly influence total laser energy requirement for capsulotomy. However, total laser energy levels were significantly higher (KW ANOVA; P < 0.001) with fibro-membranous and fibrous subtypes of PCO. Complications such as IOL pitting, intraocular pressure (IOP) elevation, uveitis, retinal detachment (RD) and cystoid macular edema (CME) were significantly more common when higher energy levels was used. The mean total energy in patients with RD was 77.7 ± 17.7 mJ as compared to 43.4 ± 26.9 mJ in the rest of the cohort. RD was more common in patients with higher axial length [n = 7 (63%)] (P < 0.001).
Type of PCO significantly influenced laser energy levels required for capsulotomy, whereas IOL biomaterial and fixation did not. Complications such as IOL pitting, uveitis, IOP elevation, RD and CME was significantly more common when total laser energy was higher. It is recommended that the lowest possible single pulse laser energy be used for capsulotomy to minimize complications.
研究影响钕:钇铝石榴石(Nd:YAG)激光晶状体囊切开术所需激光能量水平的因素,并评估所应用的激光能量水平与并发症之间是否存在相关性。
本研究连续检查了474例患者的多种因素,包括年龄、后囊膜混浊(PCO)类型、人工晶状体(IOL)的材料和固定方式以及并发症发生率,并与Nd:YAG激光晶状体囊切开术所使用的能量水平进行对比。
患者平均年龄为55.6±8.7岁,平均随访期为22.9±4.5个月。IOL生物材料(KW方差分析;P = 0.173)和患者年龄(P = 0.246)对晶状体囊切开术所需的总激光能量没有显著影响。然而,PCO的纤维膜性和纤维性亚型的总激光能量水平显著更高(KW方差分析;P < 0.001)。当使用较高能量水平时,诸如IOL点蚀、眼压(IOP)升高、葡萄膜炎、视网膜脱离(RD)和黄斑囊样水肿(CME)等并发症明显更常见。发生RD的患者的平均总能量为77.7±17.7 mJ,而队列中其他患者为43.4±26.9 mJ。RD在眼轴长度较长的患者中更常见[n = 7(63%)](P < 0.001)。
PCO类型显著影响晶状体囊切开术所需的激光能量水平,而IOL生物材料和固定方式则不然。当总激光能量较高时,诸如IOL点蚀、葡萄膜炎、IOP升高、RD和CME等并发症明显更常见。建议使用尽可能低的单脉冲激光能量进行晶状体囊切开术,以尽量减少并发症。