Bloom K K, Freed M M
Department of Rehabilitation Medicine, University Hospital, Boston University Medical Center, MA.
J Am Paraplegia Soc. 1989 Summer;12(1):11-3. doi: 10.1080/01952307.1989.11735800.
A retrospective study of serum glutamic pyruvic transaminase (SGPT) and serum glutamic oxalacetic transaminase (SGOT) was performed on eighteen previously healthy patients with acute spinal cord lesions C1 to L1 and no abdominal trauma. The SGPT rose in 13 of the 17 (76%). The SGOT rose in 8 of the 17 (47%). The SGPT and SGOT values for the entire group were significantly elevated over the upper limits of normal (p less than 0.01). The mean and median days of onset of elevated SGPT after trauma were 22 and 18, respectively. The mean and median days to normalization after trauma were 67 and 64. The mean and median days of onset of elevated SGOT were 26 and 19 respectively. The mean and median days to normalization were 42 and 43. The alkaline phosphatase were elevated in all but eight patients. The bilirubin was elevated in only three patients. Seventy-six percent of the quadriplegics and 60% of the paraplegics had elevated transaminases. The elevations are probably related to liver injury but the mechanism is unclear.
对18例既往健康、患有C1至L1急性脊髓损伤且无腹部外伤的患者进行了血清谷丙转氨酶（SGPT）和血清谷草转氨酶（SGOT）的回顾性研究。17例患者中有13例（76%）SGPT升高。17例患者中有8例（47%）SGOT升高。整个组的SGPT和SGOT值显著高于正常上限（p小于0.01）。创伤后SGPT升高的平均发病天数和中位数分别为22天和18天。创伤后恢复正常的平均天数和中位数分别为67天和64天。SGOT升高的平均发病天数和中位数分别为26天和19天。恢复正常的平均天数和中位数分别为42天和43天。除8例患者外，其余患者碱性磷酸酶均升高。仅3例患者胆红素升高。76%的四肢瘫痪患者和60%的截瘫患者转氨酶升高。这些升高可能与肝损伤有关，但机制尚不清楚。
