Van Gossum A, Seferian V, Rodzynek J J, Wettendorff P, Cremer M, Delcourt A
Dig Dis Sci. 1984 Feb;29(2):97-101. doi: 10.1007/BF01317048.
Biochemical tests (serum glutamic pyruvic transaminase, serum glutamic oxaloacetic transaminase, alkaline phosphatase, gammaglutamyltranspeptidase, bilirubin, and serum amylase) were performed upon admission in 84 patients with suspected (36) or proven (48) acute pancreatitis at the time of the first episode of acute abdominal pain suspected clinically as acute pancreatitis. These parameters all increased significantly more in patients with gallstone pancreatitis. Among them, the SGPT was the most discriminant test between biliary and nonbiliary pancreatitis. The positive predictive value of SGPT was 92%, when the cutoff point was chosen at twice the upper limit of normal. In patients with increased SGPT, a SGOT-SGPT ratio less than 1 is the rule (88%) for those with gallstone pancreatitis. This enzymatic determination allowed us to select more accurately the patients suitable for morphological procedures to confirm the biliary origin of the pancreatitis.
在84例临床疑似(36例)或确诊(48例)急性胰腺炎的患者首次出现疑似急性胰腺炎的急性腹痛时入院进行生化检查(血清谷丙转氨酶、血清谷草转氨酶、碱性磷酸酶、γ-谷氨酰转肽酶、胆红素和血清淀粉酶)。这些参数在胆石性胰腺炎患者中均显著升高。其中,谷丙转氨酶是鉴别胆源性和非胆源性胰腺炎最具鉴别力的检查。当将临界值设定为正常上限的两倍时,谷丙转氨酶的阳性预测值为92%。在谷丙转氨酶升高的患者中,胆石性胰腺炎患者的谷草转氨酶与谷丙转氨酶比值小于1是常见情况(88%)。这种酶学测定使我们能够更准确地选择适合进行形态学检查以确认胰腺炎胆源性的患者。