Shin Jung-Im, Bautista Leonelo E, Walsh Matthew C, Malecki Kristen C, Nieto F Javier
Department of Population Health Sciences, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.
Wisconsin Department of Children and Families, Madison, WI, USA.
Prev Med. 2015 Aug;77:186-90. doi: 10.1016/j.ypmed.2015.05.009. Epub 2015 May 22.
The association of food insecurity with dyslipidemia has not been firmly established. The main objective of this study was to assess whether food insecurity was associated with dyslipidemia.
A population-based sample of 1,663 adults from the 2008-2011 Survey of the Health of Wisconsin was used. Food insecurity was defined as an affirmative response to either of the questions: (1) "In the last 12months, have you been concerned about having enough food for you or your family?" (2) "In the last 12months, have your food choices been limited because there wasn't enough money?" High total cholesterol was defined as total cholesterol (TC) >240mg/dL or taking prescribed lipid-lowering medication. Low high-density lipoprotein cholesterol (HDL-C) was defined as <40mg/dL in men and <50mg/dL in women.
Food insecurity was not associated with high TC either among men or women. Food insecurity was associated with a higher likelihood of low HDL-C among women (adjusted odds ratio [AOR]: 2.31 {95% confidence interval [CI]: 1.42, 3.76}), but not among men. Obesity appears to be a partial mediator of the association among women (P from the Sobel test=0.01).
These findings suggest that food insecurity may contribute to an increased risk of low HDL-C in women.
粮食不安全与血脂异常之间的关联尚未得到确凿证实。本研究的主要目的是评估粮食不安全是否与血脂异常有关。
使用了来自2008 - 2011年威斯康星州健康调查的1663名成年人的基于人群的样本。粮食不安全被定义为对以下任一问题的肯定回答：（1）“在过去12个月里，你是否担心自己或家人没有足够的食物？”（2）“在过去12个月里，你的食物选择是否因为钱不够而受到限制？”高总胆固醇被定义为总胆固醇（TC）>240mg/dL或正在服用规定的降脂药物。低高密度脂蛋白胆固醇（HDL-C）在男性中定义为<40mg/dL，在女性中定义为<50mg/dL。
无论男性还是女性，粮食不安全与高TC均无关联。粮食不安全与女性低HDL-C的可能性较高相关（调整后的优势比[AOR]：2.31{95%置信区间[CI]：1.42，3.76}），但在男性中无此关联。肥胖似乎是女性中这种关联的部分中介因素（Sobel检验的P值 = 0.01）。
这些发现表明，粮食不安全可能会增加女性低HDL-C的风险。
