Kochoumian Elise, Kazlouskaya Viktoryia, Mangold Aaron, Lal Karan, Maia-Cohen Sandra, Elston Dirk M
New York College of Osteopathic Medicine, NY, USA.
Ackerman Academy of Dermatopathology, NY, USA.
Indian Dermatol Online J. 2015 May-Jun;6(3):217-9. doi: 10.4103/2229-5178.156422.
Combined tumors of malignant melanoma (MM) and squamous cell carcinoma (SCC) are extremely rare and have unknown biological potential. Different theories of their development, including collision and dual/divergent differentiation, are proposed. Although some observations suggest an indolent course for such tumors, a case of MM metastasis was reported in a patient who initially presented with a combined MM-SCC tumor. Re-excisions of such tumors may show MM in situ and should be treated accordingly. Herein we present another case of a combined MM-SCC tumor in a 78 male patient with lentigo maligna seen after complete re-excision of the tumor.